CURRENT STEM CELL NEWS

1. Ground breaking discovery on aging mechanism of blood stem cells

Restoration of the niche alone cannot rejuvenate blood stem cell functions, says a recent research highlighting a key role for intrinsic cell defects in stem cell aging.. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. Chromothripsis is the key culprit behind cancer cell growth – reveals study

The phenomenon known as "chromothripsis" in which chromosomes break but later reassemble has been identified to be the key factor driving cancer cell growth. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

3. Nerve stem cells with life-time renewing potential identified

A technique called intravital imaging has been employed to identify neural stem cells that can renew throughout life in the mammalian hippocampus capable of generating neurons. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. Stem cell help identify a specific signalling pathway leading to schizophrenia

Studying patient derived Human-induced pluripotent stem cells (hiPSCs) has helped pinpoint a specific signalling pathway called the PI3K/GSK3 pathway for developing schizophrenia. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. Therapeutic efficacy prediction of stem cells in limb ischemia using real-time imaging

It is possible to predict the therapeutic efficacy of endothelial progenitor cells in limb ischemia by bioorthogonally labelling these cells and tracking them through non-invasive fluorescence molecular tomography. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. Stem cells don't carry cancer-causing mutations in primitive state.

When grown in their most primitive or naive state, stem cells don't harbour cancer-related mutations, says a new study thus dispelling fears surrounding the genetic stability of stem cells. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. Molecular switch of intestinal cancer stem cells deciphered

Wnt/β-catenin signalling is crucial the maintenance of intestinal cancer stem cells. Scientists have identified the histone methyltransferase Mll1 as the key regulator of Wnt-driven intestinal cancer. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. Core set of eight proteins behind transforming stem cells to egg-cells identified

A core set of transcription factors responsible for oocyte growth has been identified and this will provide an alternative source of ooplasm for use in reproductive biology. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. Scientists modify MSC's cells surface to deliver anti-cancer drugs

Mesenchymal stem cells (MSCs)' tumor-homing ability has been utilized to load them with Anticancer drugs by modifying their cell surface for targeted cancer therapy. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. Nociceptive nerves regulate blood stem cell mobilization

Nociceptive nerves found in bone marrow help to regulate hematopoietic stem cell (HSC) mobilization and also they along with sympathetic nerves help to maintain these HSCs in the bone marrow. This study could help identify therapeutic agents to improve stem cell mobilization. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. The human genome is remarkably similar to that of Chimpanzee with only 1 percent difference. Therefore it is not the DNA sequence, but rather the regulation of the genes that plays the key role in making us humans. In a recent study scientists have precisely pinpointed the regulatory elements which act as 'gene dimmers' that makes us different from apes.
 -Source: ScienceDaily, 16 December 2020 and Science Advances, 2020; 6 (48): eabc9863 DOI: 10.1126/sciadv.abc9863

2. A study from Australia has reported that Kangaroos which have never been domesticated can intentionally communicate with humans, challenging the widely believed notion that such communicative behaviour is usually restricted to domesticated animals like dogs.    
-Source: ScienceDaily, 17 December 2020 and Biology Letters, 2020; 16 (12): 20200607 DOI: 10.1098/rsbl.2020.0607

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