Journal of Stem Cells and Regenerative Medicine

News Letter - 29                       vol.2; iss.12                              29 June 2011



1. Single signalling mechanism decides fate of stem cells

Scientists from Singapore have discovered that a single signalling pathway specifies the wide range of cell types to which a stem cell should eventually develop. Click to read more...

2. Leftover Embryonic Cells in adults may be the source of deadly esophageal cancers

A team led by Dr. Frank McKeon of Harvard Medical School and the Genome Institute of Singapore has identified that leftover embryonic cells found in all adults may be the precursor source for oesophageal cancers. Click to read more...

3. Central regulatory switch that controls the differentiation of airway basal stem cells identified

Studies have identified that the Notch signalling pathway is the central regulatory 'switch' that controls the differentiation of airway basal stem cells and this finding will pave way for therapies towards airway diseases. Click to read more...

4. Decoding marker for fat cell progenitors

Progressing towards the goal of finding methods to inactivate fat progenitor cells in the conquest of obesity, researchers have identified the first protein marker on the surface of the fat progenitor cells also known as adipose stromal cells (ASCs) and this will be of great use in targeting these cells.Click to read more...

5. Customized approach using iPS cells for retinal diseases

A team of scientists from the University of Wisconsin-Madison have generated induced pluripotent stem (iPS) cells from a human patient with inherited eye disease known as gyrate atrophy that affects the retinal pigment epithelial cells and when the gene defect in these iPS cells were corrected and when these stem cells were guided to become RPE cells, these RPE cells started functioning normally .Click to read more...

6. Mouse Gene Knockout Resource for scaling up human Gene Studies

Using a novel technique, researchers from an international consortium have knocked out almost 40 per cent of the genes in the mouse genome and the completed resource will help in gearing up studies of gene activity in models of human disease.Click to read more...

7. Phase I clinical trial using Prosthetic bypass grafts coated with patient’s own stem cells yield positive results

What might be the first of its kind, a clinical trial that uses bypass grafts lined by the patient own stem cells for peripheral vascular disease has started yielding positive results.Click to read more...

8. Key molecules behind conversion of neural stem cells to tumour stem cells in Glioblastoma explored

Researchers have identified key regulators behind the mechanism of how neural stem cells give rise to tumour stem cells of Glioblastoma, one of the most aggressive brain tumours. This has promising application in identifying novel therapies against Glioblastoma.Click to read more...

9. Tailor made human organs from Pigs: Solution to Donor organ Demand

Pigs could become human organ manufacturing factories according to the latest research in which scientists have grown rat organs in mice which lacked the ability to produce their own organs. The organs were grown from stem cells taken from the rat.Click to read more...

10. Magic gene to produce iPS Cells without cancer risk

Shinya Yamanaka and his colleagues in a joint effort with the National Institute of Advanced Industrial Science and Technology (AIST) have identified a gene ‘Glis’ that will cause the incompletely reprogrammed iPS cells to die off so that they won’t lead to cancer.Click to read more...

11. A new source of stem cells for treating brain disorders

A type of stem cells from the nose known as the human olfactory ecto-mesenchymal stem cells [OE-MSCs]) could be promising for treating brain disorders- says new study.Click to read more...

12. Brain piles up neural stem cells in response to changes in environment

Columbia researchers have found that under stressful conditions, portions of the brain produces neural stem cells and stockpile them which later may produce neurons when conditions become favourable.Click to read more...

13. Stem Cell Transplantation for multiple myeloma is an effective strategy – reveals comparative studies

A new study has reported a longer progression-free survival time with stem cell transplantation in comparison to conventional chemotherapy in multiple myeloma patients.Click to read more...


1. It is a fact that the human nose can remember 50,000 different scents

  2. Did you know that our brain is much more active at night than during the day?




1. BIT 1st Annual World Congress of Molecular & Cell Biology (CMCB-2011)
August 6-8, 2011, Beijing, China. For details Click here

2. World Stem Cell Summit;
October 3-5, 2011, Pasadena,CA. For details Click here

3. NCRM N I C H E 2011- Sixth Anniversary of Nichi-In Centre for Regenerative Medicine
Fujio Cup Quiz 2011, Plenary Session and Symposium on "Stem Cell and Regenerative Medicine",
15th October 2011, Chennai, India. For details click here

4.2nd International Conference on Stem Cells and Cancer (ICSCC-2011)
Oct 15 -19 - Pune, India.  For details Click here

5. 2nd meeting of ACTO (Asian Cell Therapy Organization)
October 17-20, Miyazaki Prefecture, Japan. For details Click here


Quote Corner:

“I have been trying to point out that in our lives chance may have an astonishing influence and, if I may offer advice to the young laboratory worker, it would be this - never to neglect an extraordinary appearance or happening ”-- Alexander Fleming


This bulletin is sponsored by


To submit your article
in JSRM click here

To advertise in this weekly
JSRM News Letter, send a
request mail to

Copyright © Journal of Stem Cells & Regenerative Medicine. All rights reserved.