CURRENT STEM CELL NEWS

1. Researchers develop human airway stem cells from patient's skin cells

Directed differentiation of human iPSCs to generate airway basal cells ("iBCs") have been accomplished which could enable modelling of acquired and genetic airway diseases. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. New approach for treating blood cancer by stopping adhesion of cancer stem cells

By abrogating the adhesion of leukemic stem cells to the bone marrow mediated by a protein called Kindlin-3 (K3), researchers have slowed down the course of leukemia in vivo. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

3. First stem cell-based model to study RNA virus diseases

Scientists have created a highly controllable viral expression model based on an iPS-cell line from a healthy human donor which enables a dose-dependent and highly localized RNA-virus expression. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. Mitochondrial membrane potential harnessed to isolate young stem cells from aged mice

Mitochondrial membrane potential (MMP) can be used to prospectively isolate chronologically old blood stem cells but having functional characteristic of young stem cells, says a mice study. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. MSCs for the targeted anti-tumour drug delivery

The cell surface of Mesenchymal stem cells (MSCs) have been modified with doxorubicin-loaded liposomes (DOX-Lips) for better delivery efficiency and anti-tumor efficacy of doxorubicin. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. Poverty associated with higher mortality in children undergoing blood stem cell transplantation

A study has identified that despite hematopoietic cell transplantation (HCT) being a curative therapy for children with cancer, stem cell transplanted children are more likely to die from treatment-related complications if they live in poorer neighbourhoods. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. Study gives insights on how mating regulates stem cell behaviour

By studying Drosophila melanogaster, a novel mechanism by which mating affects the behaviour of germline stem cells (GSCs) has been identified which helps us to understand the influence of environmental cues on stem cell niche signalling. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. Stem cells that heal broken bones can also generate arthritic bone

Fluorescent genetic cell-labelling each of eight distinct cell populations contribute to the formation of arthritic bone spurs in mice. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. Octopus inspired soft manipulator for efficient transplantation of cell and tissue sheets

A manipulator has been designed mimicking the octopus's sucker that can can lift/detach an object within 10 s and can be used repeatedly over 50 times. This would be highly useful for safe and reliable implantation of therapeutic cell/tissue sheets and biosensing devices.. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. Maintenance of regenerative capacity of muscle stem cells well beyond age deciphered

Proteins called FoxO have been found to maintain the quiescent state of muscle stem-cells until geriatric age. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. It is how active the part of the brain called the subgenual anterior cingulate cortex is, that determines how generous a person will be, says research.
 -Source: ScienceDaily, 15 August 2016 and PNAS, 2016 DOI: 10.1073/pnas.1603198113

2. Genes that regulate a hormone called Auxin have been used to develop plants that can grow deeper root systems for storing more carbon which could help scientists fight climate change.     
-Source: ScienceDaily. ScienceDaily, 11 July 2019 and Cell, 2019; 178 (2): 4000

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