CURRENT STEM CELL NEWS

1. Genetic engineering and computational modelling predicts pluripotent stem cell organization dynamics

Genetic engineering combined with computational modeling, machine learning, and mathematical pattern optimization has helped to predict how pluripotent stem cells will organize to form a tissue. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. Universal generation of therapeutic T lymphocytes from pluripotent stem cells.

Using defined transcription factors researchers have been able to generate functional and therapeutic T cells from the unlimited and editable pluripotent stem cell (PSC) source. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

3. Artificial intelligence to evaluate stem cell-derived tissue

Robust characterization methodology involving quantitative bright-field absorbance microscopy (QBAM) and deep neural networks (DNNs) have been employed to non-invasively predict tissue function and cellular donor identity of pluripotent stem cell derived retinal pigment epithelial cells (iPSC-RPE). Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. RNA levels influence embryonic stem cell differentiation

Nuclear RNA levels when in excess can have negative effects on a crucial regulator of stem cell differentiation, says a study Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. Study offers insights into retroviral silencing during cell reprogramming

One of the most important steps in the reprogramming process is the silencing of retroviruses in the human genome and now researchers have identified using a Sendai virus-based system that retroviral silencing occurred relatively early in the reprogramming process, before the development of pluripotency. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. Treating Severe Asthma by Multiple Doses of Stem Cells

Multiple doses of adipose tissue‐derived mesenchymal stromal cells (MSCs) have been found to help treat asthma by reducing lung inflammation, remodeling and also by inducing immunosuppressive effects in experimental asthma. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. Study deciphers how Omega-3 fatty acids' actually lead to health

Adult mesenchymal stem cells possess a cellular sensory organelle called the primary cilium and now a study has identified that this primary cilium senses omega-3 fatty acids in the diet which in turn affects fat stem cells' division. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. New type of Tendon stem cells discovered

Single-cell transcriptomics has helped identify (Tppp3+) cell population as potential tendon stem cells which were able to can generate new tenocytes and self-renew upon injury. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. Stem cells repair hearts by working on the immune system - suggests study

Researchers have reported that stem-cell therapies trigger immune cells called macrophages which in turn help to repair connective tissue in the damaged area of the heart that results in improvement of heart function. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. Stem cell spray treatment for heart failure

A team by Osaka University has developed a new treatment for heart failure that involves spraying of mesenchymal stem cells in adhesive solutions onto the patients' heart. Click to read more...

Really???

1. Have you heard the phrase golf is predominantly played in 'the six inches between the ears'. Yes, now research has found that kinaesthetic ability, "which is an individual's ability to feel an action without actually performing it" may actually improve how they play golf
 -Source: ScienceDaily, 27 November 2019 and Psychology of Sport and Exercise, 2020; 46: 101610 DOI: 10.1016/j.psychsport.2019.101610

2. Babies in the womb may actually see more than earlier believed. Yes, now evidence shows that light-sensitive cells in the developing retina communicate with one another through electrical connections called gap junctions whcih may contribute to the babies' retina more light sensitivity that may enhance the influence of light on behavior and brain development.     
-Source: ScienceDaily, 25 November 2019 and Current Biology, 2019; DOI: 10.1016/j.cub.2019.10.025

Creative Commons License All site content, except where otherwise noted is licensed under a Creative Commons Attribution 3.0 Unported License.