CURRENT STEM CELL NEWS

1. Universally transplantable stem cells created

Mouse and human iPSCs have been engineered to be universally transplanted and to survive in immunocompetent recipients without eliciting an immune response. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. iPS Cell clinical trial approved for spinal cord injury

The Japanese regulatory authority has approved a clinical trial on use of human-induced pluripotent stem cells (iPS) to treat spinal cord injuries. Click to read more...

3. Potential of stem cell therapy for Parkinsonism evaluated

A study has evaluated the impact of different sources and methodologies followed in stem cell-based therapies for cell replacement in Parkinson's disease. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. Antibody-based treatment for diseased blood-forming stem cells

Anti-CD117 antibody based treatment has been found to deplete human myelodysplastic syndromes (MDS) cells and facilitate transplantation of normal human hematopoietic stem cells (HSCs) thereby circumventing the use of potentially life-threatening chemotherapy or radiation to eliminate the MDS cells. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. Magnetic nanoparticles can be synthesised by human cells – reveals study

A study which observed the long-term transformations of man-made magnetic nanoparticles internalized in human stem cells has reported that nanoparticles are first degraded by the stem cells and the degradation materials such as iron are used to synthesis new magnetic nanoparticles in situ. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. New lung cancer model developed using embryonic stem cells

Human embryonic stem cells have been used to create a new model system of small cell lung cancer (SCLC) that resembled the early stages of the cancer enabling studies on identifying potential therapies for the cancer. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. Scientists develop patterned blood vessels in vitro

Human embryonic stem cell-derived endothelial cells (hESC-ECs) have been seeded into patterned microchannels which helped in developing pre-patterned vascular networks that will more efficiently support cardiac tissues after implantation. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. New virus vector for iPS cell programming

A highly efficient multi-transgene delivery system based on one-cycle measles virus (MV) vector has been used to generate genomic modification-free Induced pluripotent stem (iPS) cells. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. Complete remission in patients with peripheral T‐cell lymphomas after stem cell therapy

The first large prospective clinical study on autologous stem cell transplantation (ASCT) in patients with peripheral T‐cell lymphomas (PTCLs) has reported complete remission in the treated patients. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. Study offers Insights into regenerative potential of iPS cell derived muscle progenitors

In vitro-generated iPSC-derived muscle progenitors when transplanted inside the body remodel their embryonic/fetal molecular signature according to a new study and this knowledge will have profound implications for therapeutic applications. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. Research study suggests that women who give birth to more surviving children exhibit longer telomeres and hence age more slowly and this may be attributed to the dramatic increase in estrogen during each pregnancy.
 -Source: ScienceDaily, 8 January 2016 and Plos One, 2016; 11 (1): e0146424

2. Dog's behaviour is influenced by the Owner's behaviour as per a study. Dogs were found to be more fearful, active and less responsive to training when they had Owners with high negative emotions while the dogs were less fearful and less aggressive when their owners were extroverted and more agreeable.     
-Source: ScienceDaily, 22 February 2019 and Journal of Research in Personality, 2019; DOI: 10.1016/j.jrp.2019.01.005

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