CURRENT STEM CELL NEWS

1. Multifaceted rejuvenation of cells with novel reprogramming technique

Transient expression of nuclear reprogramming factors mediated by expression of mRNAs has been shown to reset the epigenetic clock, ameliorate cellular aging, reduce inflammatory profile in chondrocytes and restore youthful regenerative response in aged human muscle stem cells. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. Effective method to boost blood stem cell transplant

Incubation of umbilical cord blood CD34+ cells with a matricellular regulator called Nov has shown to increase the frequency of serially transplantable blood stem cells . Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

3. Study finds how connection between stem cells and neurons are implicated in cancer progression

Using Organ-on-a-chip technique, reserachers have taken cells from ameloblastomas, an aggressive mouth tumour and it has been observed that this tumour had stem cell-like properties which attracted nerves thereby leading to cancer progression. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. Supercentenarian's iPSC derived cells provide clues on aging

Donor B-lymphoblastoid cell lines (LCL) derived from a 114-year-old have been reprogrammed to derive cells which could serve as a model to understand underlying mechanisms of extreme longevity and disease resistance. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. Effective stem cell treatment system for myocardial infarction mussel protein and stem cells

A mesenchymal stem cell (MSC) based therapeutic platform using a bioengineered mussel adhesive protein (MAP) has been able to be delivered by intramyocardial injection which could distribute throughout the scarred myocardium. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. Stem cells restore damaged heart to its stage before heart attack

Stem cells in a study restored the cardiac muscle back to its condition, it was before the heart attack which could providing a blueprint of how stem cells may work. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. Multiplex printing of cells and proteins

A high-throughput method has been developed that allows simultaneous assembly of multiple cell types and ligands across length scales within minutes. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. Discovery helps untangle mysteries of how organs are formed from embryonic stem cells

Research has shown how in early stage of development, a critical protein called FoxA2 simultaneously binds to both the chromosomal proteins and the DNA thus causing gene activation. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. Trained immunity of blood stem cells

Hematopoietic stem cells (HSCs) maintain life-long production of immune cells and can directly respond to infection. Now, a study has shown that immune signaling can induce C/EBPβ-dependent chromatin accessibility, resulting in HSC-trained immunity which helps it to produce specific immune cells during secondary infection.. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. In vivo priming of stem cells using growth factor to heal hearts

An vivo priming strategy has been developed in which bone marrow mesenchymal stem cells are primed through genetically engineered hepatocyte growth factor–expressing MSCs encapsulated within an epicardially implanted 3D cardiac patch. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. Intelligence is not dependant on the grey matter alone but also the white matter according to a recent study. Also, it is not restricted to a part of the wiring alone but rather the wiring system of the brain as a whole.
 -Source: ScienceDaily, 26 March 2020 and American Journal of Psychiatry, 2020; appi.ajp.2019.1

2. It is environment and not evolution which may underlie some differences between humans and apes according to a study which claims that though researchers have claimed humans are superior to apes in social intelligence, the research environment was not valid because the research used captive adult apes against human children from rich western cities whose exposure will definitely be higher.     
-Source: ScienceDaily. ScienceDaily, 15 July 2019 and Animal Cognition, 2017; 22 (4): 487

Creative Commons License All site content, except where otherwise noted is licensed under a Creative Commons Attribution 3.0 Unported License.