CURRENT STEM CELL NEWS

1. Antioxidant to promote stem cell based bone repair after radiation damage

Stem cells primed with ferulic acid has shown to promote bone defect repair after radiation damage, by maintaining the stemness of skeletal stem cells. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. Direct reprogramming of periodontal ligament cells to endothelial, mesenchymal and bone cells

Epithelial cell rests of Malassez from the periodontal ligament of the mouth have been directly reprogrammed to progenitor stem-like cells and further into endothelial, mesenchymal stem, and osteogenic cells by stimulation with epigenetic agents. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

3. Novel marker of adult human neural stem cells identified

Neural stem cell (NSC) antibody 6 (NSC – 6 antibody) has been used as a novel marker to identify neural stem cells in the neurogenic niches of mammalian brain. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. Veto T-cells increase success rate of blood stem cell transplant in sickle cell disease

Allogeneic haematopoietic cell transplantation with anti-3rd party veto cells (which are white blood cells that have selective immunomodulation properties) has resulted in the correction of sickle cell disease in a murine model without rejection Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. Combination of chemicals generate muscle stem cells efficiently

Use of a chemical cocktail of the root extract forskolin and the small molecule RepSox has led to Skeletal muscle regeneration and expansion of myogenic stem cells within 10 days. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. Stem cell loss leads to repeated miscarriage – says study

Scientists have demonstrates that recurrent pregnancy loss is linked to the depletion of a population of highly proliferative mesenchymal cells (hPMC) in midluteal human endometrium. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. Molecular pathways behind naïve pluripotency dissected

Mass spectrometry has been employed to dissect the molecular pathways governing naïve pluripotency in embryo wherein two different circuits have been identified to be responsible for the phenomenon. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. Hydrogel creates cancer stem cell model in a day

Double-network hydrogels have been used to rapidly reprogram tumour cells into cancer stem cells which could serve as useful models for studying cancer cell types and to produce personalised therapies. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. Spherical Nucleic Acid coated nanoparticles to sort and enrich bone stem cells

Gold nanoparticles coated with oligonucleotides have been used to optically detect the specific messenger RNA (mRNA) signatures of skeletal stem cells in bone marrow enable to sort these cells for application to clinical therapies. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. Transcriptome profile of pluripotent stem cells for efficient muscle regeneration deciphered

A longitudinal comparison of the transcriptomic profiles of human induced pluripotent stem cells (hiPSCs) has helped to detail the temporal differences in mechanisms that lead to robust muscle cell specification. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. Did you know wisdom and loneliness are influenced by the microbial diversity of the gut? Researchers have found that lower levels of loneliness and higher levels of wisdom were associated with greater phylogenetic richness and diversity of the gut microbiome
 -Source: ScienceDaily, 25 March 2021 and Frontiers in Psychiatry, 2021; 12 DOI: 10.3389/fpsyt.2021.648475

2. Are you aware that playing online video games can actually make your brain more efficient in certain tasks such as sustained attention or selective attention? However, the study also shows that continuous playing may also lead to addictive "Internet gaming disorder".    
-Source: ScienceDaily, 22 June 2017 and Frontiers in Human Neuroscience, 2017; 11 DOI: 10.3389/fnhum.2017.00248

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