CURRENT STEM CELL NEWS

1. Essential genes of pluripotent stem cells mapped

In order to better understand pluripotency and lineage differentiation mechanisms of Human pluripotent stem cells (hPSCs) scientists have systematically cataloged essential genes (EGs) that are indispensable for hPSC fitness. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. Study find epigenetic regulators of embryonic stem cell state

The function of epigenetic regulators in Self-renewal and pluripotency of the embryonic stem cell (ESC) state is less well defined till now. In a new study researchers have identified two epigenetic regulators, TAF5L and TAF6L that that control self-renewal for the maintenance of ESC state. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

3. Diverse genetic mechanisms control plant stem cell proliferation – says study

For the continuous and reproducible development of plant organs, precise control of plant stem cell proliferation is necessary. A study has revealed that diverse genetic mechanisms buffer conserved developmental programs that control the plant stem cell proliferation. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. Link between gut and brain further strengthened by Growth factor study

When insulin-like growth factor II gene was depleted in mice it lead to a rapid loss of fast-cycling stem cells that replenish the gut lining along with depleting neural stem cells in brain. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. New protein study fuelling brain cancer identified

A study has uncovered that a protein called Zfp36l1 turns on biological programs which mirrors healthy early brain development but instead fuels brain cancer growth.the skin organ ageing process is rescued. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. Peptide based delivery platform for stem cells to treat heart attack

To overcome issues lower cell survival and retention in the hostile microenvironment after transplantation to treat myocardial infarction a novel self-assembling peptide (SAP) has been tested in mice to deliver mesenchymal stem cells (MSCs). Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. New gene editing technique for editing long sequences in genome developed

Researchers have used a gene editing tool called CRISPR-Cas3 to successfully delete long sequences of up to 100 kilobases of targeted DNA in human embryonic stem cells. This could help in targeting these viruses very specifically and erase them efficiently. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. Molecular signalling pathway governing muscle stem cell fate studied

A molecular signaling pathway involving Stat3 and Fam3a proteins that regulates muscle stem cell fate to self-renew or differentiate has been studied and this could help to identify techniques to promote muscle growth. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. Modified stem cells form naturel hydrogel in situ

When the membrane of human mesenchymal stem cells (hMSCs) was modified with an enzyme, known as thrombin and were placed in a solution containing fibrinogen, the cells automatically welded together through the growth of a natural hydrogel from the surface of the cells. This hydrogel could help in in tissue engineering for chronic wound healing. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. Hair follicle stem cells generate neuron covering

Melanocyte stem cells (McSCs) of the mammalian hair follicle (HF) are of two kinds CD34+ and CD34-. Researchers have identified that in culture and in vivo, CD34+ McSCs exhibited the ability to myelinate neurons. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. Sensors that detect smell in the nose have been identified also to be present in human taste cells found on the tongue. This finding suggests that primary components of food flavor may begin on the tongue and not in the brain.
 -Source: ScienceDaily, 24 April 2019 & Chemical Senses, 2019; DOI: 10.1093/chemse/bjz019

2. Scientists from Johns Hopkins undertook a survey of thousands of people who reported having experienced personal encounters with God and the results showed that a majority of respondents reported even decade long positive changes in their psychological health.     
-Source: ScienceDaily, 23 April 2019 & PLOS ONE, 23 Apr 2019 DOI: 10.1371/journal.pone.0214377

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