CURRENT STEM CELL NEWS

1. Placental stem cells heal the heart

Intravenous delivery of placental Cdx2 cells has resulted in homing of the cells to the injured heart and differentiation into cardiomyocytes significantly improving cardiac function. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. Adrenal cells renew three times more in woman- identifies study

It has been identified in female mice that there is 3-fold higher turnover of adrenal than males and this may be the reason behind increased incidence of adrenal diseases in females. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

3. Rapid method for maturing pluripotent stem cell derived heart cells

Cardiomyocytes which are derived from Human pluripotent stem cells exhibit a fetal phenotype that limits in vitro and therapeutic applications. Researchers have used a novel differentiation protocol with defined small molecule to make these cardiomyocytes mature for clinical applications. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. Cancer drugs promote colon cancer stem cells

Drugs called MEK inhibitors used to treat colon cancer inadvertently induce stem cell plasticity in the colon cancer stem cells which has been identified as the possible reason why these drugs are not effective in colorectal cancer. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. Anti-viral response of Embryonic stem cells studied

All Mammalian cells initiate a type I interferon (IFNs) response against viral infection except embryonic stem cells (ESCs) and oocytes as this response may be detrimental to development. Now researchers have studied the process by which the antiviral response is suppressed in these ESCs. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. Any cell in the intestine can become a stem cell- reveals study

Contrary to the belief that only a specific set of stem cells in the intestine have stem cell properties, a study in mice has shown that all cells of the intestinal epithelium—irrespective of their location and pattern of LGR5 expression contribute actively to the adult intestinal stem cell pool. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. Metabolic pathway changes in dysfunctional blood stem cells in Fanconi Anemia studied

Altered metabolic energetics in hematopoietic stem cells (HSCs) are observed in Fanconi anemia (FA). By studying this, researchers have narrowed upon a drug that inhibits the overactivation of a specific signal pathway which change the stem cells' energy production back to the usual pathway. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. Novel Lab technique helps create better blood vessels

A high-throughput differentiation screen was applied to a human embryonic stem cell reporter cell line and a technique was developed to make smooth muscle cells (SMCs) derived from the embryonic stem cells more contractile. This will help develop more effective artificial blood vessels in the lab. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. Wnt's role in blood development deciphered

Wnt family of molecules are a major player driving embryonic and blood cell development . Now it has been discovered that when one particular Wnt signaling molecule, Wnt9a, is received by blood stem cells, three different molecules are involved including epidermal growth factor receptor, or EGFR which is a target for many cancer therapies. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. Cell therapy for diabetes made more effective

Using single-cell sequencing a specific protein expressed uniquely by insulin-producing beta cells created from stem cells has been identified and by targeting the protein along with addition of a physical enrichment method, researchers have been able to increase the purity of beta cells upto 80%. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. Did you know that the idea to own a dog is about your genes. Yes, Swedish and British scientists who studied the heritability of dog ownership from 35,035 twin pairs from the Swedish Twin Registry concluded that genetics indeed plays a major role in the choice of owning a dog and people with the genes to own a dog have a higher innate propensity to care for a pet than others.
 -Source: ScienceDaily, 17 May 2019 and Scientific Reports, 2019; 9

2. Ever wondered how blind people learn about animal appearance? Now, a study from Johns Hopkins University study has found that adults born blind have rich insight into how different animals look like based on inference and blind people rely on similar biological classifications that scientists use to group species.     
-Source: ScienceDaily, 21 May 2019 and Proceedings of the National Academy of Sciences, 2019; 201900952

Creative Commons License All site content, except where otherwise noted is licensed under a Creative Commons Attribution 3.0 Unported License.