Journal of Stem Cells and Regenerative Medicine

News Letter - 05                       vol.1; iss.5                               19 May 2010



1. Stem Cells to Sensory Hair Cells-A Therapy for Hearing Loss?

Researchers of Stanford University School of Medicine have reported that they have found a way to induce embryonic stem cells as well as reprogrammed adult cells to develop into sensory cells that normally reside in the mammalian inner ear, a finding that justifies the development of stem cell-based treatment strategies for hearing and balance disorders

2. Physiological Oxygen Concentrations –A Determinant Of X Chromosome Inactivation In Human Embryonic Stem Cells-An exciting Discovery

According to Whitehead Institute researchers , Oxygen levels in the lab can permanently alter human embryonic stem (ES) cells, specifically inducing X chromosome inactivation in female cells, as X inactivation is vital for proper development in a female cell. If both X chromosomes are left active in an adult cell, the cell will have twice the expression of the X chromosome genes, which is fatal

3. Bone marrow stem cells- A savior for Traumatic Brain Injury

Traumatic brain injury has become identified by medical researchers as a primary candidate for stem cell study and treatment, due to the recent discoveries that some stem cells found in adult brains, when activated, could be used to repair damaged brain tissue and also some bone marrow stem cells have also been discovered through laboratory studies to be effective in generating cells to repair damage to areas that have been trauma affected

4. Cell-homing based tooth regeneration-A promising pathway for clinical translation

A new technique developed by Dr. Jeremy Mao, Edward V. Zegarelli Professor of Dental Medicine, and a professor of biomedical engineering at Columbia University, can orchestrate the body’s stem cells to migrate to three-dimensional scaffold that is infused with growth factor. This can yield an anatomically correct tooth in as soon as nine weeks once implanted in the mouth.

5. Documentation of Muscle Stem Cell movements and behavior provides insight into muscle repair mechanisms

University of Missouri researchers have used time-lapse photography to document ‘satellite cell’( stem cell found in the muscle) movements and behaviors when they interact with their 'host' myofiber which may one day help us to overcome the obstacles to cell or gene therapies for muscular dystrophy

6. Dynamic Stemness of Melanoma cells-the new hypothesis surrounding the Deadly skin Cancer

The concept of the "dynamic Stemness" of melanoma as postulated by the Scientists at The Wistar Institute can explain why melanoma cells behave like both conventional tumor cells and cancer stem cells and this might be the mechanism behind the persistent ability of melanoma ,a deadly skin cancer cells to self renew

7. Stem Cell derived Corneal tissue –A novel strategy for Drug testing
Two sets of collaborative experiments between ISCO and Absorption Systems have now shown that corneal tissue cultured by ISCO closely mimics the drug absorption and drug metabolism characteristics found in normal corneal tissue making it a promising model for studying human ocular drug absorption as an alternative to live animal testing

8. Multiple Sclerosis related Controversies ungrounded- Bone Marrow Stem Cells prove safe
A phase I clinical trial in six people with chronic multiple sclerosis (MS) investigating whether it was safe to treat them with stem cells from their own bone marrow was described by a few newspapers as controversial but the trial proved safe as it has helped stabilize the disease.

9. Problematic proteins secreted by Stem Cells in microgravity-A hurdle to space missions
A new study by Australian scientists has shown that Proteins in human stem cells grown in microgravity don't appear in stem cells grown in normal gravity and this has implications for long-term human voyages in space and it also has potential for helping solve ground-based medical problems.

10. Endometrial cells may be the key to treat Parkinson’s disease
Researchers at Yale University say they took cells from the lining of human wombs and injected them into mice with brain damage resembling those with Parkinson's disease and the scientists were able to create healthy nerve cells using endometrial cells taken from nine women who didn't have Parkinson's.

11. A trio of regulatory proteins – The Master of HSC(Blood Forming Cells) Regulation
Researchers at Rice believe that a trio of regulatory proteins controls the differentiation of hematopoietic stem cells (HSCs), the self-renewing cells the body uses to make new blood cells.




1. A Symposium on Emerging Trends in Cell Biology
School of Biological Sciences & Biotechnology
Apr 27 - 28, 2010
IIAR, Gandhinagar, India
For details click here

2010 Annual Meeting
May 22-26, 2010
Sheraton Philadelphia City Center Hotel
17th & Race Street , 19103

Philadelphia, Pennsylvania
For details click here

Bangladesh Society of Haematology
May 29, 2010
Dhaka Sheraton Hotell

Dhaka, Bangladesh

June 16 - June 19, 2010

Moscone Center
San Francisco, CA
For details click here

5. Stem Cell Global Blueprint Conference
May 21st and 22nd, 2010
MaRS Centre, 101 College Street,
South Tower, Toronto,
For details click here

6. International Seminar on “Frontiers of Stem Cell and Biotechnology
in Veterinary and Human Medicine”
15th & 16th July 2010
Madras Veterinary College
Vepery, Chennai - 600 007
For details click here

7. 5th Annual Meeting of the German Society for Stem Cell Research (GSZ)
September 30 - October 2, 2010
University of Lübeck
Campus Lübeck
For details click here

8. International Conference on Frontiers in Biological Sciences
Oct 01 - 03, 2010
NIT, Rourkela
For details click here

9. World Stem Cell Summit
Oct 04 - 06, 2010
Detroit Marriott at the Renaissance Center,
Detroit Michigan
For details click here

10. NCRM N I C H E 2010
Fifth Anniversary of Nichi-In Centre for Regenerative Medicine
Fujio Cup Quiz 2010, Plenary Session and Symposium on "Stem Cell and Regenerative Medicine",
9th October 2010, Chennai,
For details contact:

11. World Stem Cells and Regenerative Medicines Congress Asia
Oct 26 - 29, 2010
For details click here

12. International Forum on Stem Cells
Nov 12 - 13, 2010
Tianjin, Peoples Republic of China
For details click here

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1. The longest cells in the human body are the motor neurons which can be up to 4.5 feet long and they run from the lower portion of the spinal cord to the big toe in the foot

2. After Albert Einstein’s death in 1955 it seems his brain was removed for an autopsy and it was discovered that Einstein’s brain had large portion of glial cells in the region that is responsible for synthesizing information and that Einstein’s brain did not have a particular kind of wrinkle and this is believed to have allowed the neurons to communicate better with each other

3. Marie Curie has won not just one, but two Nobel Prizes: one for physics with her husband , and one for chemistry with her daughter Irene

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