CURRENT STEM CELL NEWS

1. Facially transplanted Stem cells help patients with Parkinson’s disease

Two Parkinson's patients who got local facial and nasal injections of stromal vascular fraction (SVF) showed improvement in motor scores at lower levels of dopaminergic treatment. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. Centromeres of stem cells explored

Scientists have characterized the centromeres in human stem cells and have identified that impaired centromere function may be related to stem cell aneuploidies. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

3. MSCs have long term immunomodulatory effects by reprogramming immune cells – says study

Mesenchymal stem cells have been found to reprogram the inflammatory response and have long-term effects to suppress inflammation by reprogramming monocytes and macrophages with processing bodies. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. Recommendations on stem cell transplantation for multiple sclerosis published

The National Multiple Sclerosis Society of USA has published its recommendation on Autologous hematopoietic stem cell transplant (AHSCT) for multiple sclerosis that people younger than 50 years with shorter durations of disease (<10 years) are the best candidates for the procedure. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. Scientist discover key protein that maintains healthy blood stem cells throughout life

A mRNA N6-methyladenosine (m6A) modification reader known as YTHDF2 has been found to be the key regulator that protects blood stem cells during their fight against an infection and allows them to continue functioning correctly throughout life. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. Study offers insight on neural crest stem cell fate and migration

A gene called Hmga1 has been found to play dual roles, formation of neural crest cells as well as the initiation of neural crest migration during early embryonic development. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. T cell was produced in lab using stem cell cluster

Scientists have developed a lab-grown human thymus organoid from single hematopoietic stem cells which has been able to recapitulate the murine Thymopoiesis. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. Small molecule based drug targeting for Alzheimer's disease

Researchers have identified a small molecule (10074-G5) capable of binding the disordered amyloid-ß (Aß) in people with Alzheimer's disease. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. Scientist define distinct physical hallmarks of tumour

Four distinct physical hallmarks of cancer which can affect both cancer cells and the tumor microenvironment thereby contributing tumor growth and the development of resistance to therapies have been reviewed in detail. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. Gate keeper of immune homeostasis identified

A gene called CRELD1 earlier known to play key role in the development of the heart in the embryo has now been found to be an important gatekeeper of immune system homeostasis. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. A "molecular volume knob" has been identified in the brain which can controls the width of electrical signals that flow across synapses thereby helping with learning and memory.
 -Source: ScienceDaily, 10 November 2020 and Proceedings of the National Academy of Sciences, 2020; 202000790

2. Do you know that adults with the healthiest sleep patterns have a 42% lower risk of developing heart failure according to a study done on 408802 UK Biobank Participants?     
-Source: ScienceDaily, 16 November 2020 and Circulation, 2020; DOI: 10.1161/CIRCULATIONAHA.120.050792

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