CURRENT STEM CELL NEWS

1. Potential cell therapy tools from osteoarthritis affected knee cartilage developed by Japanese scientists

Japanese scientists have accomplished to grow healthy cartilage tissues whose cells expressed pluripotency markers in the lab. These cells were cultured from osteoarthritis affected tissues obtained from elderly patients in this first of its kind study. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. Fish oil helps in major depressive disorder – iPS cell based study reveals

Supplementation with n-3 polyunsaturated fatty acids (PUFAs) helped in promotion of astrocyte differentiation and neurotrophin production of patient-derived neuronal stem cells. This study will help in identifying therapeutic strategies for Major depressive disorder . Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

3. Scientists search for neurodegeneration deficits using human retinal stem cell model.

Researchers used cells from a patient who had a genetic form of glaucoma to create pluripotent stem cells which were differentiated into retinal ganglion cells to serve as model for studying neurodegeneration deficits. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. Study deciphers earliest stages of placental development using naïve pluripotent stem cells

Derivation of trophoblast stem cells from naïve human pluripotent stem cells has been made possible which will help study early mechanisms that govern normal human trophoblast development and associated pathologies.. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. Stem cell based human gastruloid model offers blue print of embryo development

An in vitro model for early anteroposterior organization during human development has helped produce blueprint of human-specific regulatory processes that occur during early embryonic development. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. Skin tissue carrying cancer-mutations self corrects itself- says study

Adult epidermis suppresses the expansion of individual oncogenic HRAS-induced hyperproliferation in order to restrict aberrant growth and tumorigenesis.. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. Stem cell study reveal how photoaging treatment works

Autologous adipose mesenchymal stem cells when injected to photoaged Skin were able to contribute to de novo formation of oxytalan and elaunin fibers thereby leading to complete regeneration. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. Cord blood stem cell transplant better than matched sibling donor – shows study

Adult cord blood transplant actually results in better overall survival and engraftment compared to matched sibling peripheral blood transplant in a comparison study done on a large group of patients. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. Potential biomarker for screening MSC scalability identified

A study has shown that human bone marrow‐derived mesenchymal stem cells (hMSCs) containing a genomic deletion of GSTT1 show high growth capacity, clonogenicity and longer telomeres in vitro which could help to screen these MSCs for potency and scalability . Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. Stem cells help to study Neandertal DNA in modern humans

iPS cells could serve as a resource to experimentally explore Neandertal DNA function and its contribution to present-day disease phenotypes and potentially study Neandertal traits according to a recent report. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

11. β-thalassemia blood stem cells commitment is more towards RBC lineage- reveals

Immunophenotype and functional analysis of the lineage commitment of primitive HSCs/multipotent progenitor (MPP) cells in patients with β-thalassemia revealed that these cells are more committed toward erythroid differentiation. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. Land animals like humans are more smarter than their aquatic ancestors. Now it has been shown why. Complex landscapes on land with trees, bushes, boulders and knolls have helped land-dwelling animals evolve higher intelligence than their aquatic ancestors thus again proving that evolution is not based only on habit but what is in the environment too
 -Source: ScienceDaily, 16 June 2020 and Nature Communications, 2020; 11 (1)

2. Did you know that birds have a fourth colour cone in the eye that can detect ultraviolet light while humans have only three colour cones in the retina sensitive to red, green and blue light? Wild hummingbirds when studied in a series of experiments have been shown to be able to see combination colours like ultraviolet+green and ultraviolet+red.     
-Source: ScienceDaily, 15 June 2020 and PNAS, 2020 DOI: 10.1073/pnas.1919377117

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