CURRENT STEM CELL NEWS

1. Researchers successfully generate eye-like structures from stem cells

Induced pluripotent stem cell (iPSC)-derived human brain organoids have been shown to self-assemble to form optic vesicles which give rise to the eye.. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. Scientists develop method to keep cultured cells healthy

A gene called Hsf1 is essential to promote maintenance and proteostasis of blood stem cells HSC. Supplementing cultures with small molecules has helped to promote fitness of these blood stem cells in a study Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

3. Engineering polymers for controlling stem cell lineage

Engineering hydrogels with controllable and well-defined nanoscale variation in matrix stiffness cha been shown to regulate which types of cells human embryonic stem cells must develop into Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. Acetate helps reverse epigenetic changes in stem cells

Changes in the epigenome cause reduction in stem cell function especially with aging. Research has shown that acetate is a key factor in the reversal of these age related changes in isolated stem cells Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. MSC therapy effective for severe COVID-19

A recent review of clinical trials on COVID-19 has shown that mesenchymal stem cell therapy is highly tolerated and effective in alleviating lung damage in these patients Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. Safety profile of transplanted blood stem cells studied

A study has shown that majority of transplanted blood stem cells did not display altered mutation accumulation but some blood stem cells display with an increased mutation burden which has been attributed to a unique mutational signature caused by the antiviral drug ganciclovir. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. Ovarian structures reconstructed using mouse stem cells

Mouse stem cells have been used to reconstruct ovarian follicles critical for the generation of mature egg cells. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. Male germ-cells reconstituted from pluripotent stem cells

Pluripotent stem cells (PSCs) have been used to reconstitute the whole male germ-cell development in vitro needed for sperm generation Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. Robust method for creating pancreatic stem cells reported

Pancreatic progenitors (PPs) derivation in vitro at the moment is difficult to scale up at the definitive endoderm (DE) stage. Scientists have reported a robust growth-factor-free protocol for generating DE and PP cells Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. Blood stem cell mobilization using protein

By manipulating a protein called CD82 it is possible to efficiently make blood stem cells migrate into and out of the bone marrow. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. Problems in the gut microbiota especially of a bacterium called Klebsiella might be the key factor influencing certain immune cells that cause developmental neurological damage in premature babies, say scientists..
 -Source: ScienceDaily, 3 September 2021 and Cell Host & Microbe, 2021; DOI: 10.1016/j.chom.2021.08.004

2. Listening to a story with attention will synchronize your heart beat with others. An extensive research has shown that heart rates synchronize with others when subjects listened to a story but only when they paid attention. This research is important for understanding mindfulness..    
-Source: ScienceDaily, 14 September 2021. and Cell Reports, 2021; 36 (11): 109692 DOI: 10.1016/j.celrep.2021.109692

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