CURRENT STEM CELL NEWS

1. Fat cell hormone plays key role in muscle regeneration

Research has shown that cardioprotective properties of intravenously injected mesenchymal stem cells in heart failure largely depend on circulating adiponectin, an adipocyte-secreted factor. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. Endogenous virus needed for stem cells' differentiation into neuron during development

Human endogenous retrovirus (HERV-K) genes inscribed into chromosomes 12 and 19 help control the differentiation of human embryonic stem cells into neurons. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

3. Study uncovers cancer cell hierarchy beginning from a single cancer cell type

Single-cell RNA-sequencing has shown that the deadly brain cancer, glioblastoma recapitulates normal neurodevelopment and is centred around a specific progenitor population. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. RNA plays key role in cell differentiation

RNA has been identified to play a key role in cell differentiation and it serves as the bridge between genes and the "epigenetic" machinery. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. Stem cell study offers clue on gender specific diseases

A steroid hormone ecdysone from ovaries has been found to stimulate the division and expansion of intestinal stem cells in drosophila and this study throws light on sex-biased incidence of gut related diseases. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. Dynamics and geometry determines stemness

Scientist mathematically mapped noisy cell dynamics into the geometry of the organs and have been able to observe that stem cells getting to the right location in time play an essential role in determining their stemness and organ development. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. Primitive human sperm stem cells explored

Comparative RNA-sequencing analysis on primitive undifferentiated spermatogonia versus differentiating spermatogonia identified differentially expressed genes which encode for several key signalling pathways.. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. Stem cell derived exosomes as Drug Delivery system for COVID-19

Mesenchymal Stem Cell Derived Exosomes have been suggested to be an effective nano-platform foe delivering drugs and therapeutics in Combating COVID-19 due to their low immunogenicity and ability to cross the blood-brain barrier. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. Direct reprogramming creates sensory cells

A combination of four transcription factors has been used to convert mouse embryonic fibroblasts, adult tail-tip fibroblasts and postnatal supporting cells into induced hair cell-like cells which will help in developing therapies for hearing loss. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. 3D printing of human heart pump in lab using stem cells

Human induced pluripotent stem cells have been used to 3-dimensionally print electromechanically functional, chambered organoids composed of contiguous cardiac muscle. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. Favourable genetic variants that were introduced into modern humans by mixing with Neandertals, including one for progesterone receptor is the cause behind one in three European women with increased fertility, fewer bleedings during early pregnancy and fewer miscarriages.
 -Source: ScienceDaily, 26 May 2020.and Molecular Biology and Evolution, 2020; DOI: 10.1093/molbev/msaa119

2. Even a single meal high in saturated fat will hinder our ability to concentrate, says a new study and this is important especially during the COVID-19, because of changes in people diet when they work from home.     
-Source: ScienceDaily, 12 May 2020 and The American Journal of Clinical Nutrition, 2020; DOI: 10.1093/ajcn/nqaa085

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