Journal of Stem Cells and Regenerative Medicine


News Letter - 52                       vol.3; iss.13                              15 Aug 2012



1. Brain stem cells determine their fate by listening to neurons' indirect talk

John Hopkins researchers have identified that the fate of stem cells in the brain to proliferate or remain dormant is determined when these stem cells listen to the neurons communicating with each other. This is possible because of the capability of these stem cells to detect certain neurotransmitters released at the synapses at the end of the neurons. Click to read more...

2. Possible target for treating muscular diseases identified

Putting an end to the debate on which type of cells whether the satellite stem cells or the myofibres in the muscle are the target for the potential drug for muscular diseases, the myostatin, a study has identified that myostatin's action does not significantly involve satellite stem cells. This is important because satellite stem cells are depleted in patients with muscular diseases and this study suggests that myostatin can be of help in these patients too. Click to read more...

3. Cardiac cells derived from Human Embryonic stem cells can beat in synchrony- proves animal study

Cardiomyocytes derived from human embryonic stem cells injected in injured hearts in animal models of guinea pigs have shown to integrate with the animal's heart tissue both in normal areas and in areas with scar tissue. The integrated cells showed promising results as these cells in the normal areas of the heart beat in synchrony with the animal's heart.Click to read more...

4. Aurka, an Oncoprotein's role in Embryonic Stem Cell and induced pluripotency studied

Researchers have identified that the protein kinase Aurora A (Aurka) is an essential component of embryonic stem cells' self-renewal ability. This oncoprotein has been shown to be amplified in several tumours and this study has shown that this oncoprotein exerts its action by inactivating the well known tumour suppressor gene p53. Click to read more...

5. Cancer stem cells do exist- Points out experimental evidence

Two separate studies published in the journal "Nature" has pointed with evidence that a population of cancer stem cells do exist in the cancers and these cells are responsible for the re-growth of the tumours. Click to read more...

6. Fate of neurons in the brain's cortex linked to a stem cell population rather than their timing of birth

The cerebral cortex in the brain is the seat of higher functions in humans and it has several layers of neurons. Earlier it was thought that neurons of each layer of the cortex were derived from the same stem cells that produce different type of neurons at different points in time during development. Now a study has shown that there is a separate progenitor cell for the upper layer neurons. Click to read more...

7. Molecule that makes breast cancer cells resistant to chemotherapy by reversion to stem cell like state, identified

Breast cancer cells when they turn into a stem cell like state become hormone independent and resistant to chemotherapy. Now a microRNA molecule that plays a role in the reversal of these cancer cells into the stem cell like state has been identified, making it a suitable therapeutic target for treating cancer.Click to read more...

8. Post-injury arthritis could be prevented by stem cells - Says study

Using highly purified mesenchymal stem cells, researchers from Duke University Health System have proven that it is possible to prevent the development of arthritis in mice after injury.Click to read more...

9. Blood vessels from skin cells created in just two weeks improves leg function in ischemic leg in an animal model

A new study has demonstrated that vascular cells developed by reprogramming skin cells in just two weeks, can help improving leg function when injected into the ischemic leg of an animal model. Click to read more...

10. Pluripotency of stem cells not affected by cryopreservation even for 18 years - Study reveals

Researches from Thailand have shown in their study that human embryos cryopreserved and stored for 18 years can yield viable embryonic stem cells after thawing and these cells could prove a valuable resource for drug screening and research. Click to read more..


1. Did you know that the partially synthetic bacterial cell created at the J Craig Venter's Institute, had watermark sequences which were coded messages in the form of DNA base pairs to distinguish the synthetic organism from natural organism? In the minimal genome project from the same laboratory, the names of the researchers were included as watermarks.

2. Do you know how animals adapt to sub-zero temperatures? It is because these animals use various biochemical processes including anti-freeze compounds to adapt and live in these environments. The interesting fact is researchers have now identified one of the most active anti-freeze compounds isolated till date called Xylomannan in an Alaskan beetle and more interesting is that this compound is based on glycan in contrast to other anti-freeze compounds which are usually protein based.




1. Stem Cells in Cancer and Regenerative Medicine; 29th August to 1st September 2012 Heidelberg, Germany. For details Click here

2. SPINE 2012 , 13 - 16th September, 2012, Le Royal Meridian, Chennai For details Click here.

3. International Conference on Tissue Science and Engineering; 1st to 3rd October 2012, Chicago, Illinois, United States of America. For details Click here

4. NCRM NICHE 2012, 13 Oct, 2012, Savera Hotels, Chennai For details Click here.

5. Nov 29-30, 2012; 7th Annual ConGress of the German Ssociety for Stem Cell Research, Leipzig, Germany. For details Click here.



Quote Corner:

"It's far more important to know what person the disease has than what disease the person has."

- Hippocrates



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