CURRENT STEM CELL NEWS

1. More efficient Biosensors to characterize stem cells developed

A unique biosensing platform consisting of array of ultrathin graphene layers and gold nanostructures has been developed to detect genes and characterizes different kinds of stem cells with greater reliability & efficiency. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. Researchers grow fully functional lungs in mice using transplanted stem cells.

Successful generation of functional lungs in mice has been reported where the scientists employed conditional blastocyst complementation (CBC) approach of donor mouse pluripotent stem cells (PSCs). Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

3. Heart attack model developed using human stem cells

Though there are model animals for cardiac diseases there have been concerns about difference in heart rate, action of drugs etc based on differences in gene expression between lab animals and humans. To overcome this researchers have developed a mouse model of ischemic heart disease using cardiomyocytes differentiated from human induced pluripotent stem cells (hiPSC). Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. New drug to expand umbilical cord blood for stem-cell transplants

A clinical trial has shown the benefits of a drug called UM171 for cord blood stem cell expansion which allows for the use of small single cords without compromising engraftment. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

 

5. Spaceflight alters genes in human stem cells

Cardiomyocytes made from human induced pluripotent stem cells (iPSCs) were sent up to the International Space Station with astronauts and RNA sequencing revealed that many genes in the cells were expressed differently than ones on earth including genes for mitochondria metabolism. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. Short wave of hematopoietic stem cell production in late fetus/young adult.

Haematopoietic stem and progenitor cells (HSPCs) generation was thought to be restricted only to the early stages of development. Now a bone marrow haemogenic endothelium in the late fetus/young adult has been documented whose cells are capable of de novo producing a cohort of HSPCs in situ. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. Dental stem cells can generate mammary gland cells – shows study

Dental epithelial stem cells (DESCs) were observed to adopt all the possible mammary fates including milk-producing alveolar cells in a recent study. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. Scientists study how stem cells forget their past

Researchers have discovered that transcription factors may be more analogous to being the memory of the cell and once the as the transcription factors are removed, the cells can no longer return to their point of origin. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. Plectin – a potential biomarker for lung cancer stem cell identified

Overcoming the paucity of reliable biomarkers for cancer stem cells (CSCs), Plectin has been identified as a biomarker for lung CSCs and high plectin mRNA expression has been shown to be associated with poor patient survival in lung adenocarcinoma. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. Stem Cell Transplant for Neuromyelitis Optica

Stem cell transplant has helped treat a debilitating neurological disease known as neuromyelitis optica (NMO) in a human clinical trial. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. Contrary to the belief that boys do maths better, new research which has comprehensively examined the brain development of young boys and girls has revealed that there no intrinsic biologic difference between the genders and boys and girls engage the same neural system during mathematics development.
 -Source: ScienceDaily, 8 November 2019 and npj Science of Learning volume, 2019 DOI: 10.1038/s41539-019-0057-x

2. By examining the cord blood it is possible to predict psychological development of kids, says a study. Yes, newborns's whose cord blood showed high levels of high-density lipoprotein (HDL) were more likely to receive higher ratings on psychological development at 5 years of age by their teachers.     
-Source: ScienceDaily, 13 November 2019 and Psychological Science, 2019; 095679761988564 DOI: 10.1177/0956797619885649

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