CURRENT STEM CELL NEWS

1. Brain organoids that produce brain waves created in lab

Stem cells have been used to create miniature brains in vitro that developed functional neural networks and these are the first organoids ever created observed to produce brain waves that resemble those of preterm babies. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. iPS derived cornea transplanted to humans

Sheets of corneal cells from induced pluripotent stem (iPS) cells have been created and transplanted to a woman with corneal disease in first of its kind clinical study. The patient's cornea remained clear and her vision had improved after the month of transplant. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

3. iPS derived neural cells to treat Gaucher disease

Intravenous infusion of induced pluripotent stem cell-derived neural precursor cells in a mouse model of Gaucher Disease was found to increase the acid β-glucosidase function in the brain and lessens the neuronopathic phenotype. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. Stem cell platform helps study early embryonic development

Controlled modelling of human epiblast and amnion development using pluripotent stem cells has helped create an in vitro platform which can help study the earliest stages in human development and also to study if a drug can be safe for a pregnant woman in the earliest stages. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. Gene edited stem cells tried for HIV treatment

CRISPR-Edited Stem Cells have been used for the first time in a Patient with HIV and Acute Lymphocytic Leukemia. The gene-edited cells survived in the man's body for more than a year but the number of cells was not high enough to significantly reduce the amount of HIV in his blood. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. Allogeneic stem cell transplantation for multiple myeloma – Long term results published

A trial compared tandem autologous stem cell transplantation (autoSCT), autoSCT and allogeneic stem cell transplantation (auto/alloSCT) in multiple myeloma patients with follow-up of more than 7 years and the results showed that auto/alloSCT significantly extends progression-free survival compared to tandem autoSCT. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. Scientist design Islet-on-a-chip that allows continuous monitoring of insulin-producing cells,

A thermoplastic, microfluidic-based Islet on a Chip has been developed which automates islet loading, stimulation, and insulin sensing along with mimicking the perfusion of native islets by designated arterioles and capillaries by delivering synchronized glucose pulses to islets positioned in parallel channels. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. Discarded Eel skin derived collagen for 3D printing

Discarded eel skins have been used to fabricate 3D scaffolds for tissue engineering application and the Eel skin derived collagen scaffolds can serve as excellent alternative to expensive and land animal derived collagen materials. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. Technology to transplant cells to brain without rejection

Scientists have developed a new approach, which selectively circumvents the immune response against foreign cells thus allowing transplanted cells to survive, thrive and protect the brain without immune rejection. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. Reactivating the in-active X chromosome could help treat genetic disorders- suggests study

Researchers present new findings on X chromosome reactivation during induced pluripotent stem cell reprogramming which could help to treat Rett syndrome and other genetic disorders linked to the X chromosome.. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. Scientists have now shown why people tend to gain weight as they grow older. The study revealed that regardless of whether a person gained or lost weight, there is decrease in lipid turnover (the rate at which fat is removed from fat cells and stored) in the fat tissue as we age. So people who don't compensate eating by exercise tend to gain weight by 20 percent or more.
 -Source: ScienceDaily, 9 September 2019 & Nature Medicine, 2019; 25 (9): 1385

2. Researchers have identified differences in genetic components and architecture in the brain that leads to left-handedness and also, the study suggests that in left-handed participants, the language areas of the left and right sides of the brain communicate with each other in a more coordinated way thus raising the intriguing possibility that left-handers might have an advantage when it comes to performing verbal tasks.     
-Source: ScienceDaily, 4 September 2019 & Brain, 2019; DOI: 10.1093/brain/awz257

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