CURRENT STEM CELL NEWS

1. Amniotic stem cells for better treatment to ischemic stroke

The therapeutic potential of human amniotic fluid stem cells (hAFSCs)‐derived secretome has been investigated in an ischemia/reperfusion in vitro model. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. Tetrahertz light pulses change gene expression in stem cells

Tetrahertz pulses generate an electric field which has been found to activate or deactivate the genes in human induced pluripotent stem cells. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

3. New biomarker to help overcome graft rejection in stem cell transplantation

Specific subsets of dendritic cells called ICOSL+ plasmacytoid dendritic cells have been identified to be inducers of graft-versus-host disease after stem cell transplant. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. Tweaking metabolism in hair stem cell niche to prevent hair loss

Hair follicle stem cells (HFSCs) niche can return to their stem cell state only if suppression of a metabolic switch from glycolysis to oxidative phosphorylation and glutamine metabolism occurs. By deleting mTORC2 which critical for this metabolic switch researchers have been able to regulate the niche. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. New molecule stimulates stem cells to reverse periodontal disease.

Lipid mediators such as Maresin-1 (MaR1) and Resolvin E1 (RvE1) have bene shown to restore or improve the regenerative properties of human periodontal ligament stem cells (hPDLSCs) even in the presence of inflammation. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. New discovery quantifies regenerative potential of highly potent blood stem cells from human embryo

A single human hematopoietic stem cell (HSC) from Aorta-gonad-mesonephros (AGM) region can generate 600–1,600 functional daughter HSCs according to a study which has for the first time been able to exactly quantify the regenerative potential of the human embryo-derived HSCs. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. Promising approach for treating spinal cord injury using stem cells

Expression of a factor called OLIG2 in ependymal cells, which function as stem cells of the spinal cord has been able to make these cells aid in axon remyelination and improved axon conduction after spinal cord injury.. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. Novel nanoparticles to turn off genes in bone marrow cells in vivo

Systemically injected lipid–polymer nanoparticles encapsulating small interfering RNA (siRNA) has been used for the silencing of genes in bone-marrow endothelial cells which helped improved healing after infarction and attenuated heart failure. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. Study reports rapid harvesting of stem cell sheets in two days

Rapid harvesting of human bone marrow mesenchymal stem cells (hBMSCs) sheets in two days has been possible by using thermoresponsive bulk poly(N-isopropylacrylamide) (PNIPAAm) nanotopography. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. Scientists study embryonic stem cell-specific heterochromatin state in depth

Scientists have studied the mechanism of a special type of heterochromatin which is used by embryonic stem cells to silence 'parasitic' DNA-elements within the context of their highly dynamic pluripotent chromatin. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. Women who delivered their last child later in life are likely to have a longer life, scientists have reported using study of maternal age at last birth and leukocyte telomere length.
 -Source: ScienceDaily, 7 October 2020 and Menopause, 2020

2. Study of single neurons have revealed that the activity of these individual cells can show how confident we are in our decisions.     
-Source: ScienceDaily, 9 October 2020 and Current Biology, 2020

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