Table 4. Improvements in BMAC and HA Group Secondary Outcome Scores Relative to Baseline

Outcome
Measure

Group

Time

n

Mean (SD)

Mean DifferenceA
(95% CI)

p-valueA

Mean DifferenceB (95% CI)

p-valueB

NPRS

BMAC

Baseline

17

4.59 (1.84)

-

-

0.39 (-0.82, 1.59)

0.528

 

3 mo

15

2.67 (2.55)

-1.92 (-3.27, -0.57)

0.005

-0.05 (-1.67, 1.57)

0.947

 

6 mo

14

2.14 (2.18)

-2.45 (-3.60, -1.28)

<0.001

-0.67 (-2.07, 0.73)

0.345

 

12 mo

13

1.46 (1.51)

-3.13 (-3.96, -3.29)

<0.001

-1.57 (-2.89, -0.25)

0.020

 

HA

Baseline

15

4.20 (1.70)

-

-

 

 

 

3 mo

15

2.33 (1.99)

-1.87 (-2.76, -0.97)

<0.001

 

 

 

6 mo

14

2.43 (1.55)

-1.77 (-2.55, -0.99)

<0.001

 

 

 

   12 mo

14

2.64 (2.02)

-1.56 (-2.59, -0.53)

0.003

 

 

PROMIS

BMAC

Baseline

17

44.62 (7.61)

-

-

-3.62 (-8.95, 1.72)

s0.184

Physical

 

3 mo

15

49.24 (6.51)

4.62 (0.84, 8.41)

0.017

4.04 (-1.73, 9.80)

0.170

 

 

6 mo

14

51.38 (6.89)

6.76 (3.63, 9.89)

<0.001

3.27 (-1.31, 7.84)

0.162

 

 

12 mo

13

49.38 (4.72)

4.77 (1.99, 7.54)

0.001

1.51 (-3.05, 6.07)

0.517

 

HA

Baseline

15

48.23 (7.99)

-

-

 

 

 

 

3 mo

15

48.82 (14.16)

0.59 (-3.76, 4.94)

0.791

 

 

 

 

6 mo

14

51.73 (8.57)

3.50 (0.16, 6.83)

0.040

 

 

 

 

12 mo

14

51.49 (9.38)

3.26 (-0.36, 6.88)

0.077

 

 

PROMIS

BMAC

Baseline

17

51.88 (5.02)

-

-

-0.02 (-5.23, 5.19)

0.995

Mental

 

3 mo

15

49.71 (4.93)

-2.18 (-3.87, -0.48)

0.012

-1.52 (-6.31, 3.27)

0.533

 

 

6 mo

14

51.87 (6.19)

-0.01 (-3.25, 3.23)

0.995

-2.25 (-6.53, 2.02)

0.301

 

 

12 mo

13

51.95 (4.93)

0.07 (-2.64, 2.77)

0.959

-2.94 (-7.29, 1.42)

0.187

 

HA

Baseline

15

51.90 (9.36)

-

-

 

 

 

 

3 mo

15

51.25 (14.78)

-0.65 (-5.13, 5.83)

0.775

 

 

 

 

6 mo

14

54.14 (7.86)

2.24 (-0.54, 5.03)

0.114

 

 

 

 

12 mo

14

54.91 (9.75)

3.01 (-0.40, 6.42)

0.084