Journal of Stem Cell & Regenerative Medicine
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Autologous Immune Enhancement Therapy

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Vol.IV  Issue: I: Abstract: PASRM 2008-004 (JSRM code: 004010700006) Full Text pdf

Autologous Immune Enhancement therapy for Advanced Carcinoma of Pancreas-A Case Report

Sivaraman G1, Pandian A2, Baskar S3, Senthil KR3, Senthilnagarajan R3, Srinivasan V3, Dedeepiya V3, Abraham S3,4

(PASRM** 2008-004)

1. Shrusti Hospital, Chennai, India. 2. Deepam Hospital, Chennai, India. 3. Nichi-In Centre for Regenerative Medicine, Chennai, India. 4. Yamanashi University - Faculty of Medicine, Chuo, Japan

Introduction: Autologous Immune Enhancement therapy (AIET) is one of the lesser used modality of therapy in our country for advanced cancers. AIET uses patientfs own immune cells such as NK cells and T-Lymphocytes to fight against cancer.

Aim: To study the effectiveness of AIET in Advanced Carcinoma of pancreas.

Case History: A 40 years old male was diagnosed with inoperable locally advanced Carcinoma of the head of pancreas when he was investigated for obstructive jaundice. Palliative bypass surgery was done, since his tumor was inoperable. Following his surgery he received 6 cycles of adjuvant chemotherapy and 3 cycles of AIET.? After completion of chemotherapy and 2 cycles of AIET therapy his tumor marker decreased significantly with decrease in tumor size.? So re-laparotomy was attempted for removal of tumor, which was unsuccessful. After a long gap he received his 3rd cycle of AIET.? He was irregular in receiving his AIET treatment. He survived for 18 months after the diagnosis.

Conclusion: The median life span of patients following diagnosis of advanced Carcinoma of pancreas is usually not more than 3-6 months. Longer survival of our patient could be due to AIET, but we need further studies to prove it. There were no adverse effects encountered due to AIET.


Corresponding Author: Dr.G.M.Sivaraman, MS, MRCS (UK) Consultant General & Laparoscopic Surgeon, Srushti Hospital, #1 Padmavathy Street, Thirumalai Nagar, Ramapuram, Chennai-600089. India. Tel:+91-44-24864748.;


** Proceedings of Annual Symposium on Regenerative Medicine

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