CURRENT STEM CELL NEWS

1. Unique stem cells found in resting zone of bone

Researchers have identified a type of skeletal stem cell in the "resting zone" of the epiphyseal growth plate which is initially unipotent and acquires multipotency at the post-mitotic stage. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. Ischemia induced stem cells best for stroke therapeutics

A careful comparison between ischemia-induced, multipotent stem cells (iSCs) and bone marrow-derived mesenchymal stem cells (BM-MSCs) has shown that the iSC characteristics make them more promising candidates as CNS injury therapeutics. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

3. Skeletal stem cells reverse to development state for extensive regeneration

A mouse model of a surgical procedure used in humans to correct an undersized lower jaw has helped understand that the process of bone distraction makes adult mouse skeletal stem cells in the jaw revert to a more developmentally flexible state for aiding regeneration. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. Scientists grow functional 3D tissue model of brain for study

Functional and sustainable 3D Human Neural Network models have been developed in the lab from Pluripotent Stem Cells.Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. Promoting blood cells regeneration using mesenchymal stem cell (MSC) secretome

MSCs cultured on polydimethylsiloxane (PDMS) substrata were found to promote haematopoiesis in an in vitro co-culture model with hematopoietic stem and progenitor cells (HSPCs) and systemic administration of mechanoprimed MSCs helped in more efficient hematopoietic recovery. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. New Cell Transplantation Results in Structural and Functional Recovery in cerebral palsy

In an animal model of cerebral palsy, injection of neural precursor cells into the corpus callosum demonstrated recovery of lesions in the corpus callosum as well as the hippocampus and the cortex and improved walking and limb use. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. Autonomic nervous system controls somatic stem cell proliferation

Scientists have found evidence for a direct effect of the autonomic nervous system on intestinal epithelial stem cell proliferation. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. Scientist find how growth of milk-producing mammary glands is triggered during puberty

Sleeping stem cells in the mammary gland are awoken by a protein dubbed FoxP1 which switches off the production of one of the key proteins that keep mammary stem cells asleep. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. New stem cell research provides solution for restoring fertility in men after childhood cancer treatment

Transplantation of testicular endothelial cells (TECs) alone has been shown to restore spermatogenesis in mice after chemotherapy-induced depletion of Spermatogonial stem cells (SSC). Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. Scientist achieve unisexual reproduction of mouse using stem cells and gene editing

By deleting 3 genetically imprinted regions in parthenogenetic haploid embryonic stem cells (ESCs) restored normal growth of fertile bimaternal mice and deletion of 7 imprinted regions in androgenetic haploid ESCs enabled production of live bipaternal mice that died shortly after birth. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. Did you know that removing the appendix early in life reduces the risk of developing Parkinson's disease by 19 to 25 percent as the appendix acts as a reservoir for disease-associated proteins.
 -Source: ScienceDaily, 31 October 2018 and Science Translational Medicine, 2018; 10 (465): eaar5280

2. A study of hundreds of years of family trees have identified that it is man's genes that play a role in him having sons or daughters. A man with many brothers is more likely to have sons, while a man with many sisters is more likely to have daughters.     
-Source: ScienceDaily, 12 December 2008 and Evolutionary Biology, Dec 11, 2008 DOI: 10.1007/s11692-008-9046-3

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