CURRENT STEM CELL NEWS

1. First iPS clinical trial for heart disease approved

Japan has approved the first clinical study on the treatment of severe heart disease using heart sheets derived from induced pluripotent stem (iPS) cells. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. Stem cell therapy leads to vision loss in three women

Three patients have developed severe bilateral visual loss after they received intravitreal injections of autologous adipose tissue–derived "stem cells". Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

3. Microengineered pluripotent-cell-based model to understand neural development

A micropatterned human pluripotent stem (hPS)-cell-based neuroectoderm developmental model has been generated by scientists which helped to study the biomechanical principles that guide neuroectoderm patterning. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. In utero blood stem cell therapy helps live birth of an infant with an otherwise fatal fetal condition

Researchers have safely transplanted mother's stem cells into her growing fetus who was diagnosed with alpha thalassemia major, leading to the live birth of the infant. Click to read more...

5. Crosstalk between breast stem cells and macrophages deciphered

A recent study has identified that Notch pathway ligand is enriched in mammary gland stem cells (MaSCs) and this mediates critical interactions with stromal macrophages in the surrounding niche.Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. Robots perform complicated stem cell experiments in lab

An automated robotic system has successfully completed a complicated experiment testing out the effects of a drug or genetic manipulation on pluripotent stem cell derived lab-grown kidneys. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. Embryonic breast stem cells' development studied

The timing and the mechanisms mediating early lineage segregation of multipotent stem cells during breast gland development in the embryo has been studied . Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. Blood stem cells can compensate for B and T cell deficiencies – says study

Scientists found that the normal blood stem cells can compensate for the B and T cell deficiencies by over-producing the specific cell type which is deficient thus helping to maintain a balanced immune system. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. World's first 3D-printed cornea developed

Human cornea has been bio-printed using in-house collagen-based bio-ink containing encapsulated corneal keratocytes. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. Space's microgravity weakens muscle formation - reveals study

Simulated microgravity has been observed to weaken muscle formation (myogenesis) by controlling DNA methylation status of Myod1. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. The reason why genetic changes behind bigger brains that made us human have been elusive. Now scientists have shown that the gene family, NOTCH2NL is specific for human brain development and may have been a driving force in the evolution of our large brains.
 -Source: ScienceDaily, 31 May 2018 and Cell, 2018; 173 (6): 1370

2. The microbes in our gut could hold the secret to longevity according to a new research which has shown that a combination of probiotics and an herbal supplement was able to prolong the flies' longevity by 60 percent and protect them against aging associated chronic diseases -Source: ScienceDaily, 31 May 2018 and Scientific Reports, 2018; 8 (1)

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