CURRENT STEM CELL NEWS

1. Stem cell derived retinal organoid sheets see the light of the day

Human embryonic stem cell (hESC)-derived retinal sheets have been shown to integrateand improve visual function in rat models of retinal degeneration paving way for clinical trials to be started soon on these lines. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. Embryonic stem cells (ESCs) alleviate Parkinson's disease in monkeys

Embryonic stem cells (ESCs) transplanted into the brains of neurotoxin-induced Parkinson's disease monkeys has produced variable but apparent behavioral improvement for at least 24 months in most monkeys. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

3. Immunotherapy using CAR engineered Human iPSC-derived NK cells

New CAR constructs have been used to optimize targeted anti-tumor activity of Human iPSC-derived NK cells to provide an "off-the-shelf" resource for cancer therapy. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. Immune cell population behind intestinal inflammation identified

A discrete population of effector CD4 T cells that is able to both sustain and confer intestinal inflammation have been identified . Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. Small molecule to create mature blood cells in the lab

By implementing an adherent culture, serum-free differentiation system, scientists have utilized a small molecule CHIR99021 to induce Human Pluripotent Stem Cells toward various hematopoietic lineages. .Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. Human embryonic stem cell derived astrocytes enter clinical trials

A Phase 1/2a clinical trial has been started to test the safety and effectiveness of human embryonic stem cell-derived astrocytes in patients with amyotrophic lateral sclerosis (ALS), after positive results were seen in animal models of the disease. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. Artificial intelligence to sort disease specific pluripotent stem cells

Computational machine learning methodology has been used to accurately categorize Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) developed from patients with different genetic cardiac diseases and this could provide effective methods for diagnostic purposes in the future. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. Fat stem cells' role in fighting obesity in humans reviewed

A review has shown that in spite of promising beneficial effects of adipose-derived mesenchymal stem cells (AD-MSCs) on obesity well documented in animal models, further well-designed studies should be performed in the future for translating the technology to humans. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. Cell carrying robots developed

A magnetic microrobot has been developed for carrying and delivering targeted cells inside the body. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. Role of fibroblast growth factor in sperm stem cell differentiation deciphered

A novel function of fibroblast growth factor 2 (FGF2) has been observed in the mammalian testis. Although both factors glial cell line-derived neurotrophic factor (GDNF) and FGF2 are the self-renewal factors for spermatogonial stem cells (SSCs) in vitro, this study has revealed that FGF2 acts to facilitate the differentiation of spermatogonial stem cells (SSCs) in vivo. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. Similar to animals like sea lions, red deer, and dogs which use vocalizations to judge one another's size and physical formidability, a new research has shown that humans too judge other humans by inferring from nonverbal vocal cues such as aggressive roars and aggressive speech sentences.
 -ScienceDaily, 28 June 2018 and iScience, 2018; DOI: 10.1016/j.isci.2018.05.002

2. Did you know that a recent study has reported that crystalline particles of titanium dioxide a most common white pigment found in everyday products ranging from paint to candies may actually be linked to the rapid rise in the number of people suffering from Type 2 diabetes?
-Source: ScienceDaily, 20 June 2018 and Chemical Research in Toxicology, 2018; 31 (6): 506

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