CURRENT STEM CELL NEWS

1. Signalling factor inhibition in stem cells to treat Muscular Dystrophy

The muscular potential of skeletal muscle progenitor cells (SMPCs) derived from Human pluripotent stem cells (hPSCs) can be improved by inhibition of transforming growth factor-ß signalling during differentiation. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. Chemical cocktail to create muscle progenitors in lab

miRNA cocktails that promote the myogenic potential of Human Mesodermal iPSC-derived progenitors (MiPs) have been defined in a recent study. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

3. Drug to treat iron overload to rescue stem cell niche in blood cancer

Bone marrow vascular niches which sustain the blood stem cells can be rescued with the small molecule deferoxamine, which is normally used to treat iron overload for promoting chemotherapeutic efficacy and enhancing the survival in Acute myeloid leukemia (AML). Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. Study offers insights into cell differentiation mechanisms behind stomach cancer

A study has found evidence that gastric cancer cells can develop even in the absence of stem cells by direct differentiation of the chief cells of the stomach. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. Molecular mapping of embryonic stem cell reversal to totipotent state analysed

Researchers have studied the process by which gene expression changes and regulation help pluripotent embryonic stem (ES) cells to reprogram back to a two-cell embryonic totipotent-like state.Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. Key proteins behind naïve pluripotency revealed

Two 'finger-like' proteins of the PRDM family have been found to safeguard the naïve pluripotency of embryonic stem cells which helps them to differentiate into a variety of cell types. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. Comparative genome studies between Salamander and mammals helps unravel clues to regeneration

Comparative genomic study has shown that a gene called Pax3 is necessary for development of muscle in Salamander while it is not needed for mammalian muscle regeneration. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. Bio-ink for Bioprinting refined using novel technology

Drop-On-Drop method has helped to stabilize Bio-ink used in a cell compatible inkjet bioprinting method to bioprint human tissues and organs. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. Silk used for creating human intervertebral disc

Mulberry silk has been employed to fabricate a spinal biodisc construct which mimics the human intervertebral disc in form and function. Click to read more...

10. Streamlined method for cardiac cell differentiation

Scientists have found a simple method to make stem cells develop to heart cells by turning off a single gene. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. Scientists have found that it is the region of the brain called piriform cortex, a part of the olfactory brain which is the one involved in the process of saving memories triggered by smell but it can work only when signals come from orbitofrontal cortex indictaing that it is a memory to be stored for a long time..
 -Source: Science Daily and Cerebral Cortex, 2017

2. Sperms can help treat gynaecological cancers. Yes, Researchers have harnessed the swimming power of sperm to carry a cancer drug directly to a cervical tumor in lab tests.     
   -Source: Science Daily and ACS Nano, 2017

Creative Commons License All site content, except where otherwise noted is licensed under a Creative Commons Attribution 3.0 Unported License.