CURRENT STEM CELL NEWS

1. Lab grown liver tissue kept viable for more than an year

In vitro generated 3D cellular aggregates of liver cells were found to exhibit stable phenotype for over one year in culture. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. Stem cells found to be safe for ALS Patients

A clinical trial has established the safety of IV and spinal canal-delivered (intrathecal route) mesenchymal stem cells derived from the bone marrow in patients with Amyotrophic Lateral Sclerosis (ALS). Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

3. New procedure grows astrocytes from stem cells more effectively

Overexpression of the transcription factors SOX9 and NFIB in human pluripotent stem cells results in rapid and efficient generation of homogeneous populations of induced astrocytes. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. New approach uncovered for expanding blood-forming stem cells

A new study has identified the role of mRNA reader YTHDF2 in adult hematopoietic stem cell (HSC) maintenance and has also found that it plays an important role in regulating HSC ex vivo expansion.Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. Hydrogel loaded stem cells to treat muscle trauma

A synthetic hydrogel-based matrix loaded with Muscle satellite cells (MuSCs) has been found to have enhanced survival, proliferation, and engraftment in muscles of aged and dystrophic mice. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. Vision restored after muller glia derived retinal cell transplantation

A recent study has provided evidence of vision restoration after de novo Müller glia (MG) -derived genesis of rod photoreceptors in mammalian retinas. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. Spinal cord bioengineered using iPSC derived neural progenitors

A bioengineered spinal cord has been fabricated using 3D bioprinting, in which clusters of induced pluripotent stem cell (iPSC)‐derived spinal neuronal progenitor cells (sNPCs) and oligodendrocyte progenitor cells (OPCs) were used. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. Rare nervous system disease modelled in the lab using stem cells

Alexander disease (AxD) which affects astrocytes has been modelled in the lab using patient iPSC-derived astrocytes which recapitulate key features of AxD pathology. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. Stem cells throw light on mechanism underlying Sudden unexplained death in epilepsy

Dravet syndrome (DS) in which there is a high incidence of sudden unexpected death in epilepsy (SUDEP) have been modelled in vitro using induced pluripotent stem cell-derived cardiac myocytes (iPSC-CMs) from DS patients which has shown that the high risk of SUDEP in DS may result from cardiac arrhythmias which occur in these patients in addition to seizures. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. Intra-cavity stem cell therapy inhibits brain tumor progression

Brain-derived Cytotoxic neural stem cells (NSCs) and novel induced NSCs (iNSCs) generated from pediatric skin when delivered into the surgical cavity effectively targeted residual medulloblastoma foci. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. One in five human genes which were believed to be functional may not be according to a new study which has established that the total number of protein coding genes in humans has been revealed to be 20 percent smaller than earlier known number.
 -Source: ScienceDaily, 30 August 2018 and Nucleic Acids Research, 2018; 46 (14): 7070

2. The reason behind humans being more intelligent with bigger brains has been attributed to the mammals trading the ability to give rise to a bigger litter of offspring for brain power.     
-Source: ScienceDaily, 29 August 2018 & Nature, 2018; DOI: 10.1038/s41586-018-0441-3

Creative Commons License All site content, except where otherwise noted is licensed under a Creative Commons Attribution 3.0 Unported License.