CURRENT STEM CELL NEWS

1. Pre-Clinical study of neural progenitor cells in primates show success

Human spinal cord–derived neural progenitor cells (NPCs) were injected into sites of cervical spinal cord injury in rhesus monkeys and there was improvement in forelimb function after grafting. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. Mutations in skeletal muscle genes cause age related decline – study shows

Somatic mutagenesis in satellite cells (SCs)which the resident stem cells has been found to be the driving force in the age-related decline of skeletal muscle (SkM) function. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

3. Cardiosphere-Derived Cells and their exosomes improve muscle function in mouse model of Duchenne Muscular Dystrophy

Cardiosphere-derived cells (CDCs) and exosomes secreted by CDCs have been shown to improve cardiac muscle function, walking abilities and survival in a mouse model of Duchenne muscular dystrophy. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. Neural stem cells (NSCs) reprogrammed from somatic stem cells repress neuro-inflammation - Hope for treating Multiple sclerosis

Somatic cells and NSCs obtained from reprogramming the somatic cells have been proven to decrease ameliorate chronic CNS inflammation by reducing succinate levels in the cerebrospinal fluid, thereby decreasing immune cell infiltration and secondary CNS damage. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. Age of stem cell donor crucial for successful bone marrow stem cell transplant

A new study has identified that even after genetic matching, the age of a stem cell donor is very important factor influencing patient survival following a blood stem cell transplant.Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. Dual mechanism maintaining embryonic stem cell pluripotency identified

Researchers have identified two pathways — polycomb repressive complex (PRC2) and embryonic stem cell-specific cell cycle (ESCC) regulating microRNAs which suppressed the expression of the endocytosis-associated genes in embryonic stem cells that actually helps them maintain their pluripotency state. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. Progenitors of pancreatic cells discovered

Multipotent cells expressing PDX1 and ALK3 have been identified in the human exocrine pancreas which have been found to have the ability to differentiate into multiple pancreatic lineages. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. Alveolar epithelial progenitor (AEP) - A potential cell population for human lung regeneration

A recent study has uncovered a Wnt-responsive alveolar epithelial progenitor (AEP) cell population in the lung which has the ability to rapidly regenerate a large proportion of the alveolar epithelium after acute lung injury. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. Stem cells bioengineering to treat pelvic prolapse

Endometrial mesenchymal stem cell have been combined with nanobiomaterials in a world-first approach to develop more effective treatments for pelvic organ prolapse. Click to read more...

10. Antibody based Clinical trial for Bubble Boy disease shows promise

An antibody to CD117, a cell surface marker has been employed in a phase-1 trial involving participants who have severe combined immunodeficiency to wipe out their defective blood stem cells without high-risk chemotherapy or radiation. Click to read more...

Really???

1. A scientific survey has shown that people who are easily disgusted by body odors actually have political views in which they like to have a dictator-like leader who can ensure that different groups "stay in their places and this instinct might probably would have arisen from a deep-seated instinct to avoid infectious diseases.
 -Source: ScienceDaily, 27 February 2018 and Royal Society Open Science, 2018; 5 (2): 171091

2. Did you know that by seeing the neural activity itself it is possible to predict who your friends are? Researchers have found that friends had the most similar neural activity patterns, followed by friends-of-friends who, in turn, had more similar neural activity than people three degrees removed (friends-of-friends-of-friends).     
-Source: ScienceDaily, 30 January 2018 and Nature Communications, 2018; 9 (1)

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