CURRENT STEM CELL NEWS

1. Allogenic mesenchymal stem cells to treat poor graft function after blood stem cell transplantation

As an adjunct therapy to allogenic hematopoietic stem cell transplantation (HSCT), researchers have administered mesenchymal stem cells from third party donors to the patients who had poor graft function after allo-HSCT. The results have reported a positive outcome. Click to read more...

2. Immunotherapy using altered T cells can help to achieve remission in leukemia patients- suggests study

Patients with acute lymphoblastic leukemia (ALL), a deadly blood cancer, when infused with their own T cells altered outside the body to express a particular protein receptor had a total remission. This adoptive T cell therapy is being advocated as a bridge to bone marrow transplant in such ALL patients. Click to read more...

3. Novel nano-tracking methodologies to enhance stem cell therapy

Researchers at Stanford University School of Medicine in California have used silica nano-particles to track the injected stem cells into the heart using ultrasound as silica is ideal for back-scattering the sound waves. This technology has helped researchers to identify the ideal region for injecting the stem cells.Click to read more...

4. Mesenchymal stem cells grown in low oxygen tension and along with chondrocytes produce cartilage with better qualities

A study has shown that when mesenchymal stem cells (MSC) from Bone marrow are cultured at low oxygen tensions and along with cartilage cells, the correct proteins are produced in the culture which in turn results in a cartilage with better elastic properties akin to native cartilage. Click to read more...

5. Multipotent stem cells from deer antlers – A valuable source for regenerative therapies in veterinary medicine

An interesting work has been published on the differentiation of deer’s antler tissue-derived multipotent stem cells into various lineages. This study suggest that deer antler tissue is a valuable source of stem cells which can be potentially useful of regenerative therapeutics in veterinary science. Click to read more...

6. Study offers insight into signalling pathways behind menstrual blood stem cell proliferation

A team lead by Kazemnejad et al have explored the Wnt signalling pathway which plays a major role in the proliferation of the menstrual blood stem cells, which are an unique source of stem cells. This molecular study will be useful in developing successful therapies using these stem cells. Click to read more...

7. Engineered protein to enhance blood stem cell expansion in vitro

Weill Cornell researchers along with Memorial-Sloan Kettering Cancer Center researchers have used a modified form of a protein called HOXB4 to increase the proliferation of these blood stem cells to several folds in vitro. Click to read more...

8. Amniotic fluid stem cells to repair the gut – A potential breakthrough

As a potential solution to Necrotizing Enterocolitis (NEC) , a deadly disease that affects the gut, in newborns especially, researchers have injected amniotic fluid derived stem cells into rats with NEC and the results showed that these stem cells helped in reducing the inflammation and improving the gut function.Click to read more...

9. Tracing the origin of olfactory neurons that help in smell yield valuable clues

A team of biologists at the California Institute of Technology (Caltech) have found that olfactory neurons which are responsible for the sense of smell actually develop from the neural crest. This study is important as understanding the origin of these cells will help in identifying therapeutic solutions for conditions like anosmia or inability to smell. Click to read more...

10. Reversible epigenetic changes in blood stem cells explored – Turning back the clock in aged stem cells possible

A research group at Lund University in Sweden have successfully rejuvenated and reprogrammed the blood stem cells in aged mice by utilizing certain reversible epigenetic pathways in these blood stem cells. Click to read more..

Really???

1. Did you know that in most functional aspects, humans have more genes compared to other animals except in the aspect of metabolism in which the "mustard weed" (Arabidopsis) has a higher number of metabolic genes than any other animal sequenced till date, including the humans?

2. Are you aware of the first clinical trial recorded in the history of mankind? It is the legume trial described in the “Book of Daniel” in The Bible. King Nebuchadnezzar during his rule had ordered his subjects to eat meat and drink only wine which he thought would be the ideal food. However as some young royals objected this and wanted to eat vegetables, the king ordered these rebels to eat legumes and water for 10 days. After ten days, as the king observed that these vegetarians were better nourished than those who ate meat, the king permitted the advocates of legume to continue their diet.

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