CURRENT STEM CELL NEWS

1. iPSC technology offers insight into differences in pathogenesis of Alzheimer’s disease between patients

Researchers from Japan have used patient specific Induced pluripotent stem cell (iPS) technology to model Alzheimer’s disease (AD) from sporadic and familial AD patients and their results show differences in pathogenesis and response to treatment between individual patients. Click to read more...

2. Novel Gene therapy to direct the heart muscle to secrete factors that will recruit stem cells to the site of injury

A Florida based Clinical trial has been started to use gene therapy to direct heart muscle cells to secrete a protein called SDF-1 thereby recruiting circulating stem cells to the site of injury for preventing the ongoing cell death and for restoring the blood flow. Click to read more...

3. Stem cells in Schistosome worms may help them live long, decades after infecting a host- identifies study

Schistosome worms the cause of the most common schistosomiasis infection have been studied by researchers who have identified that these worms have stem cell like cells similar to the Planaria worms and these stem cells may be the reason behind how these worms live for long inside the host.Click to read more...

4. Novel strategy to target specific stem cell niches in bone marrow - Hopes to improve efficacy of chemotherapy

Findings of a recent study in mice have revealed that the niches that support the blood stem cells and the immune cells are different. Differential targeting of these niches could help in cancer therapies and improving the success of stem cell transplants. Click to read more...

5. Heart tissue engineering using parthenogentic stem cells of human egg

Using chemicals to induce parthenogenesis, a form of asexual reproduction in human eggs, researchers have obtained stem cells from these eggs and also used them to tissue engineer heart muscle in a breakthrough approach. Click to read more...

6. A sugary way to coax stem cells

Researchers have employed sugar coated scaffolds to induce stem cells to differentiate into particular cell types and this approach will help design future strategies for coaxing stem cells to turn into the cell of need. Click to read more...

7. Embryonic stem cells from mice to be sent to space for experiments

AAn ambitious mission, the SpaceX Dragon capsule to be sent to the International Space station has an added package. It is going to carry embryonic stem cells from mice which will be exposed to stretches of space during the mission and once back on earth will be used seeded in female mice to study the effects of long time space travel in the offsprings created from these stem cells. Click to read more...

8. Researchers employ Donor T cell infusion to prevent post stem cell transplant relapse

Researchers at Fred Hutchinson Cancer Research Center have employed adoptive transfer of donor T lymphocytes, taken from the stem cell donor itself, cultured in the lab using special cocktails, in patients who underwent stem cell transplant for leukemia. The results indicate that these T cells help in anti-leukemic response and these patients survived without relapse for more than 30 months.Click to read more...

9. Stem cells from the bone marrow to treat Inflammatory Bowel disease

As a possible treatment for the Inflammatory Bowel Disease (IBD), Wake forest university researchers propose to use a combination of two stem cell populations in the Bone marrow capable of producing new blood vessels and modulating the inflammation to treat IBD. Click to read more...

10. Identification and culture of Liver stem cells accomplished

In a study published in the journal Nature, Scientists have reported the identification of liver stem cells using Wnt induced Lgr5 marker expression and they were able to grow these liver stem cells in large numbers in the laboratory. These lab grown liver stem cells were even transplanted in mouse model with results showing modest therapeutic effects. Click to read more...

Really???

1. We all know that we the modern day human’s taxonomic name is Homo sapiens. Did you know the etymology for Homo sapiens? Homo in Latin stands for “human being, man"; sapiens for "wise, sensible, judicious".

2. Do you know what a Suicide Gene is? This gene will cause a cell to kill itself through apoptosis. The main protein switch for this gene is the p53 protein. Suicide genes are being explored for Cancer therapies and also for molecular cloning.

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