CURRENT STEM CELL NEWS

1. Potential for airway stem cells in lung regeneration explored

Using a mice model, researchers have found that a type of a type of adult lung stem cell known as p63+/Krt5+ when transplanted, proliferate and contribute to regenerating alveoli near the site of the lung inflammation. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. Cardiac stem cells for repairing heart damage in Duchenne muscular dystrophy

In a recent study when cardiac stem cells were injected in mice with Duchenne muscular dystrophy, there was marked improvement in the heart function. Click to read more...

3. Scientists find way to trap cells in a" self-renewing" state

A team of researchers have identified a method by which it is possible to keep mouse progenitor cells in an immortal-like state using six transcription factors. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. Alternate way to target enzyme in blood cancer found

A mutation in the gene that codes for an enzyme called Abl-kinase causes hyperactivity of the enzyme leading to a type of blood cancer known as chronic myeloid leukemia. Drugs are targeted towards this enzyme but the treatment becomes ineffective due to cancer cells becoming resistant. Now scientists have reported an alternate portion in the Abl-kinase where drugs can bind and act, thereby reducing risk of resistance development in cancer cells. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. Role of signaling molecule in neural stem cell regulation identified

Scientists have identified a signaling molecule that controls the potency of neural stem cells and this molecule helps the neural stem cell to switch between early and late phases of nerve cell development. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. Pain sensing neurons created in a dish using skin cells

Using five genes, researchers have successfully converted mouse and human skin cells to pain sensing neurons in the lab that respond to a number of stimuli causing acute and inflammatory pain. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. WNT signaling is required for cellular reprogramming- reports study

While studying induced pluripotent stem cells (iPSC) to create a "disease-in-a-dish" model of a rare inherited skin disorder, scientists have uncovered a signaling molecule which is crucial to cellular reprogramming and this study has great implications in regenerative therapies. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. Remotely controllable magnetic nanoparticles for bone regeneration shows promise

In a recent study, scientists have used magnetic nanoparticles coated with targeting proteins and controlled them remotely in order to stimulate stem cells in an injured area to regenerate bone. Click to read more... |Click here to view the link of the relevant publication in a peer reviewed journal

9. Combined therapy using lipoic acid and bone marrow derived cells for brain injury

Bone marrow derived cells when combined with Lipoic acid (anti-oxidant) application has resulted in potent blood vessel formation in the damaged areas of the brains of laboratory mice. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. Novel population of nail stem cells with bi-functional stem cell qualities identified

A new population of stem cells in the nail has been discovered and these cells possess bifunctional abilities. These cells normally were able to contribute to formation of nail structure and the layer surrounding the nail but after an injury the balance tilts towards nail regeneration. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. Did you know that diet induced obesity alters the function, structure and potency of adult stem cells from a variety of tissues? In fact it has been identified that in obese women, their stem cells make breast cancer grow faster compared to slim women.
  - Source: Wu et al. Int J Obes (Lond). 2013 and New Scientist article 2013 by Colin Barras

2. Are you aware that there studies which have reported that there is impairment in the immune system after acute sessions of prolonged high intensity exercises and athletes actually face a high risk of infection? This impairment in the immune system is profound when there is no food intake during exercise.
                                                                     - Source: Wikipedia and Gleeson Journal of Applied Physiology 2007

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