CURRENT STEM CELL NEWS

1. iPS technology harnessed to create first human model of pancreatic cancer progression

As a solution to the search for a suitable cell model of early-disease progression in pancreatic cancer, researchers have used iPS technology to create the first of its kind cell line from a patient with advanced pancreatic ductal adenocarcinoma (PDAC). Click to read more...

2. Study offers insight into the mechanism how neural stem cells create varied type of neurons

A new study has examined how a select group of stem cells in the brain of fruit fly can create progenitors that then sequentially generate numerous subtypes of nerve cells thus opening new avenues in understanding neural diversity. Click to read more...

3. Patient specific stem cells to treat maturity-onset diabetes of the young (MODY)

Patient-specific insulin-producing cells, that accurately reflect the features of maturity-onset diabetes of the young (MODY) have been created from MODY patients and correction of the gene defect has shown to restore insulin secretion to levels seen in cells obtained from healthy subjects.Click to read more...

4. Stem cells combined with apoptosis blockers for improved wound healing

Regulatory protein that stop apoptosis, or cell death, called inhibitors of apoptosis proteins (IAP) when combined with stem cells have been shown to hasten healing in mice with artificially created skin injuries. Click to read more...

5. Healthy blood stem cells ignore a particular gene mutation while cancerous blood stem cells don't! Surprising finding in a study.

A team of scientists from the NYU Langone Medical Center have discovered a novel method way to target leukemia by studying the mechanism of a mutated protein, called Fbxw7 which affects only cancerous blood stem cells but not healthy blood stem cells. Click to read more...

6. Biowire technology helps maturation of heart cells derived from human pluripotent stem cells

Researchers can now create mature cardiac patches for clinical application in a faster and reliable manner, thanks to the study done by researchers from Toronto which showed that electric pulse delivered to stem-cells derived human cardiomyocytes when seeded along a silk biowire suture can make the cells to mature and beat like a real heart tissue. Click to read more...

7. Targeted gene therapy helps destroy breast cancer stem cells- Potential tool to combat deadly breast cancer

A novel engineered virus has been created which can deliver modified genetic material, the mda-7/IL-24 gene with its encoded protein directly to breast cancer stem cells thereby decreasing their proliferation without affecting normal breast stem cells.Click to read more...

8. Stem Cell transplant for Myelodysplastic Syndromes revisited

Mathematical models have been employed to analyze hundreds of Myelodysplastic Syndromes (MDS) cases from around the world in a study and the results have revealed that reduced-intensity stem cell transplantation actually offers a survival benefit in patients with higher-risk MDS, but not for those with lower-risk disease. Click to read more...

9. Nanog promotes tumour progression by stimulating cancer stem cell proliferation

A new study has demonstrated that a protein called Nanog, which is active in embryonic stem cells helps in the promotion of the growth of cancer stem cells in head and neck cancers and this study will help in designing targeted therapies for these cancers. Click to read more...

10. Shockwave treatment makes body to produce more stem cells and fastens healing- says study

A team of scientists recently presented in a conference that medical shockwave treatment can stimulate the organisms to produce more stem cells which can be used in the self-healing process thus reducing recovery times and treatment costs. Click to read more..

Really???

1. Did you know that artificial synapse has been created by Japanese scientists using a single nanoscale electrochemical atomic switch and the most exciting part of the research is that the synaptic device they have created essentially mimics major features of human cognition like "emulation of synaptic plasticity" including what happens in long term and short term memory? The device also has ability to respond to presence of air and temperature changes thus indicating that it can possible perceive the environment like the human brain. This invention is considered as a giant leap towards creation of artificial brain.

2.Of serendipitous discoveries in Biology, the discovery of relationship between pancreas and diabetes needs mention. In 1889 two German physicians Joseph von Mering and Oscar Minkowski in order to study role of pancreas in digestion did so by removing pancreas in dogs. Several days after, they observed that the urine secreted by these dogs was swarmed by flies. Later they understood that it is because these dogs whose pancreas was removed were secreting sugar in their urine, thus finding out for the first time, the link between pancreas and Diabetes.

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