CURRENT STEM CELL NEWS

1. Scaffold mediated gene delivery for cartilage regeneration

A team of researchers has devised a new scaffold mediated therapy for replacement of cartilage tissue in which they incorporated viruses to deliver the gene to the stem cells, into a synthetic material that serves as a template . Click to read more...

2. Long term safety of stem cell based gene therapy proven in Epidermolysis Bullosa

Researchers here evaluated a patient with Epidermolysis Bullosa (EB) seven years after he underwent a stem cell-based gene therapy and the results have proven the safety and efficacy demonstrated by restoration of normal skin function. Click to read more...

3. Rhythmic pulsation is the driving force for cardiac muscle cells to form heart valves - says study

It has been identified that rhythmic expansion and contraction of cardiac muscle cells is essential for the endothelial cells to transform into valvular interstitial cells (VICs) for formation of heart valves. Click to read more...

4. Muscle stem cells from elderly mice rejuvenated by targeting p38 MAP kinase signalling pathway

Blocking the biological cascade called the p38 MAP kinase pathway in stem cells from aged mice while growing them in vitro in a hydrogel scaffold made them to divide rapidly iand produce new stem cells that can robustly repair muscle damage, according to a new study.Click to read more..

5. Study throws light on processes that occur in embryonic cells during implantation

Scientists have not been able to study what happens to the cells in the embryo during implantation. Now employing right conditions outside the womb to study the implantation process, researchers have observed for the first time that the blastocyst becomes a 'rosette' of wedge-shaped cells during implantation. Click to read more...

6. Cell therapy using patient's own immune cells lead to complete remission in adult B cell acute lymphoblastic leukemia (B-ALL) patients

Results of a clinical trial in adult B cell acute lymphoblastic leukemia (B-ALL) patients has shown that 14 of the 16 patients who were treated with genetically modified versions of their own immune cells achieved complete remission. Click to read more...

7. Abd-B gene function study throws light on basic regulatory mechanisms of differentiation of germline stem cells in Drosophila

In a study on Drosophila it has been shown how a special developmental gene called Abd-B gene from the Hox family influences germline stem cells that form sperms and that impairment of this gene function resulted in prematurely aged sperms. Click to read more...

8. Nine months follow-up demonstrated continuing functioning of liver cells derived from skin cells in mice study

A new method has been reported to transform human skin cells into mature fully functioning liver cells and nine months after these cells were transplanted into mice, it was observed that the cells continued to function.Click to read more...

9. Tissue engineering Scaffold created using decellularized human fibroblasts

So far scaffolds have been made from synthetic materials or natural animal or human substances. In a recent study, fibroblasts have been coaxed to form highly aligned nanofiber scaffold and this scaffold has an added advantage of provoking a very low immune response. Click to read more...

10. Cell migration of normal and cancer cells depends on nuclear stiffness - reports study

Researchers have reported after studying normal cells and cancer cells that cell migration through micron-size pores is regulated by lamin-A, a nuclear protein and also that cell nuclei with low levels of lamin-A were relatively less stiffer. Also when a cell squeezes its nucleus through a small pore, cell death is triggered when lamin-A is low. Click to read more..

Really???

1. Of serendipitous discoveries, the discovery of chicken cholera vaccine by Pasteur deserves mention. Pasteur isolated microbes from the chicken with the cholera and when these microbes were injected into new chickens, those chickens died. Pasteur keen on finding a mechanism for preventing the disease tried whatever possible to the isolated microbe broth or the chickens but couldn't succeed. Pasteur then tired, went on a vacation and asked his assistants to inject more chickens with the next batch of bacteria. The assistants neglected the task and the bacteria which sat down for weeks when injected into chickens, the chickens did not die. Also when new batch of bacteria were injected into these chickens, the chickens did not die while chickens that hadn't previously been injected with the "spoiled" batch of bacteria all died thus giving rise to world's first attenuated vaccine

2. Did you know why cells were termed cells? When very thin slices of bottle cork were first observed by Robert Hooke in 1665 under a coarse, compound microscope, he observed a multitude of tiny pores that looked like the walled compartments, a monk would live in and hence Hooke called them cells, the name they still bear.                                                                 
                                                                                                                                                      Source – Wikipedia

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