CURRENT STEM CELL NEWS

1. Embryonic stem cells explored to understand molecular basis of totipotency

Researchers have reprogrammed embryonic stem cells using a novel technique which has helped them to understand how those cells develop characteristics resembling a totipotent zygote. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. Micro-RNA basis of radiation resistance of esophageal cancer stem cells revealed

Using an in vitro model of radiation resistant esophageal cancer, it has been shown that the cancer stem cells of this cancer had low levels of a particular microRNA which when synthetically replaced made the cancer cells more sensitive to radiation. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

3. Synthetic hybrid mixture for selective removal of iPS cells developed

Using a fluorescent chemical probe, a chemically tractable molecule has been discovered which can selectively remove undifferentiated human induced pluripotent stem cells (hiPSCs) in cell mixtures, as these undifferentiated cells have risk of tumourigenicity. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. Improved longevity of retinal cells achieved using immunosuppression

Long-term vision has been restored in blind mice by transplantation of embryonic stem cell derived retinal cells with blocking the immune response which may otherwise lead to rejection of the transplanted cells. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. Role of tumour suppressor gene in maintaining muscle stem cells deciphered

Modifying the expression of a gene PTEN gene could help in proper maintenance of muscle stem cells and in the future may improve therapies for muscle injuries. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. iPS based retinal transplants improve vision in mice

Transplanting mouse iPSC-derived retinal tissue (miPSC retina) in a retinal-degeneration mouse model has helped restore vision in almost half of the mice. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. Protein to enhance bone healing in Diabetics

Delivery of a factor called TNFα has helped in activating bone stem cells that helps repair fractures in diabetic mice. Click to read more... | Click here to view the link of the relevant publication

8. Small molecule help teeth repair by stem cells

According to a new study, specific small molecule antagonists can help promote teeth to repair themselves in mice. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. Novel drug treatment to combat GVHD through maintenance of T cell function

Combined inhibition of two signalling pathways can promote the differentiation of potent regulatory T cells to prevent GVHD after stem cell transplants. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. Stem cells to regenerate heart's outer layer

Treating pluripotent stem cells with chemicals which sequentially activate and inhibit Wnt signaling pathway can help in formation of epicardial cells which form the outer muscle layer of the heart. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. Are you aware that antibiotics in addition to creating resistance in bacteria can actually mutate bacteria like E-coli to make them reproduce faster?
    
 -Source: ScienceDaily, 30 January 2017 and Nature Ecology & Evolution, 2017; 1: 0050

2. Did you know why when we blink, the lights actually don't dim? It is because when we blink our brain works overtime to reposition our eyeballs so we can stay focused on what we're viewing.    

-Source: ScienceDaily, 19 January 2017 and Current Biology, 2017

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