CURRENT STEM CELL NEWS

1. Factor behind homing of blood stem cells identified

A factor called Pleiotrophin might be the long sought growth factor of blood stem cells as it helps in regeneration and homing of blood stem cells to the bone marrow which will be particularly useful after chemotherapy, bone marrow transplants and anti-Pleiotrophin antibody causes existing blood stem cells to leave bone marrow and enter blood stream which will be useful in mobilizing these cells from the bone marrow for use in stem cell transplants. Click to read more...

2. Brain tumour turns brain cells to cancer stem cells and thereby grow aggressively - says study

As a possible explanation on why brain tumours called Glioblastomas are difficult to treat, Scientists have identified that by introducing cancer genes even neural cells can revert back to Glioblastoma producing cancer stem cells. Click to read more...

3. Study identifies novel monocyte-macrophages that protect blood stem cells from exhaustion during alarm situations

Even during situations such as stress and Chemotherapy, some of the blood stem cells continue to survive and remain as stem cells. The mechanism behind has been attributed to a novel monocyte-macrophage population which release certain substances and protect the blood stem cells from differentiation during stress.Click to read more... 

4. Novel method to replace Mitochondrial DNA in Human egg cells developed- Potential option to prevent inherited diseases due to defects in mitochondria

Offering a potential solution for prevention of occurrence of inherited diseases causes due to defects in Mitochondria, researchers have successfully swapped the mitochondria in the cytoplasm of a Human egg cell with mitochondrial defects and that of a healthy egg cell. Click to read more...

5. LRRK2 mutation plays major role in development of Parkinson’s disease - Reprogramming approach offers valuable clues

Creating neural stem cells using the reprogramming approach, from Parkinsonism patients with a mutation in LRRK2 gene has helped scientists understand the underlying the disease mechanism as to how this mutation deforms the membrane surrounding the nucleus of a neural stem cell leading to the development of the disease. Click to read more...

6. Insights into embryonic stem cell biology

A team led by Carnegie's Yixian Zheng has identified that a protein called Utf1 plays a major role in embryonic stem cell renewal and rapid proliferation by acting through three different mechanisms. Click to read more...

7. Micro RNA to help replenish blood cells after Chemotherapy

The study on the role of a Micro RNA named miR-150 in regulating the formation of blood cells has offered a potential target to help replenish the blood cells after Chemotherapy which usually destroys these blood cells.Click to read more...

8. Amniotic fluid cells help regenerate blood vessels

Amniotic fluid cells have been reprogrammed directly to endothelial cells that line the blood vessels and these endothelial cells were founded to form stable vasculature in a study done by researchers from Weill Cornell Medical College.Click to read more...

9. Cells challenged by Pathogens assume greater plasticity- reveals study

The role of Virus in gene delivery for reprogramming does not stop with the delivery alone. Rather, it has been found that challenging the cell with the virus helps loosen its chromatin giving increasing access to its DNA and this process increases the reprogramming efficiency. Click to read more...

10. Cartilage cells created from iPSCs

Researchers have been successfully able to create cartilage cells from Induced Pluripotent stem cells and this study would lead to development of patient-specific cell and tissue models to screen for drugs to treat osteoarthritis. Click to read more..

Really???

1. Did you know that the famous Immortal cell line used in research, the HeLa cell line is being considered as a separate species called Helacyton gartleri by a biologist named Leigh Van Valen due to its properties like chromosomal incompatibility with humans, its ecological niche, having an own clonal Karyotype and their ability to persist and expand well beyond the desires of human cultivator?

2. Among Genes with fancy names, have you heard about a gene named POKEMON which may act as a master switch for cancer? However the Gene was later renamed as Zbtb7 due to threatened legal action by the Pokemon Company.

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