CURRENT STEM CELL NEWS

1. Tendon stem cells to heal tendon injuries

Tendon stem may help to improve tendon healing by regulating inflammation in treatment of acute and chronic tendon disease. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. RNA molecule acting as protector against breast cancer identified

Researchers have identified a microRNA called miR-199a which helps mammary gland stem cells (MaSCs) suppress the production of a protein called LCOR thereby leading to increased normal stem cell function which prevents cancer stem cell formation. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

3. PDGF critical for hair stem cell function – says study

Platelet-derived growth factor (PDGF) has been identified to be critical for driving self-renewal and proliferation of dermal stem cells in hair follicles which makes them continuously regenerate to produce new hair. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. From Sterile to Fertile – Stem cells create miracle

Germline stem cells taken from a young mouse and implanted into the ovary of a mouse that had been sterilized has helped the sterilized mouse to become pregnant and deliver healthy offspring. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. Novel Cocktails to produce blood stem cells reported

Two studies published recently have come up with cocktails to produce blood stem and progenitor cells from pluripotent stem cells and also the adult endothelium or lining of the blood vessel. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. Different subsets of iPS cells detailed

Since iPS cell lines are genetically and phenotypically heterogeneous a research team has now studied 711 iPS cell lines and have provided detailed overview of their genetic and phenotypic variability. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. Rare psychomotor disease modelled using iPS

The defective blood brain barrier in Allan-Herndon-Dudley syndrome (AHDS), a psychomotor disease has been modelled in the lab using induced pluripotent stem (iPS) cells. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. p53 mutations – a risk for stem cells

Human pluripotent stem cells (hPS cells) are an attractive source for regenerative therapies but when they grow indefinitely in the lab they have risk of acquiring dominant negative TP53 mutations which are most commonly seen in human cancers. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. New protocol helps efficient derivation of microglia

A robust, efficient method has been reported by researchers for deriving microglia, the immune cells of the brain. It is important to note that microglia are implicated in disorders such as Alzheimer's disease, Parkinson's disease and multiple sclerosis. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. Novel hydrogels influencing stem cell differentiation reported

Researchers have fabricated gradient hydrogels with continuous linear gradients which help to pinpoint optimal stiffness which will help in precisely control the behaviour of stem cells growing on them. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. Are you aware that our brain has a caloric thermostat that regulates our weight? Yes, in a mice study, scientists have found that specific neurons called 'agouti-related neuropeptide' (AGRP) neurons are the main contributors to the caloric thermostat which regulate our system to eat when hungry and spare energy when food is not available.    
 -Source: ScienceDaily, 23 May 2017 and eLife, 2017; 6 DOI: 10.7554/eLife.22848

2. Did you know that actual information from the real world never reaches the brain through our eye? Yes, a study has found out that that when choosing between two identical visual objects one generated internally and the other externally, our brain has a bias towards the internal information. So it is all finally about perception.    
-Source: ScienceDaily, 16 May 2017 and eLife, 2017; 6 DOI: 10.7554/eLife.21761

Creative Commons License All site content, except where otherwise noted is licensed under a Creative Commons Attribution 3.0 Unported License.