CURRENT STEM CELL NEWS

1. Chemically Induced Pluripotent Stem (CiPS) Cells – A new paradigm in iPS research

Reprogramming of adult cells by addition of extra genes can lead to risks such as mutation and cancer formation. To overcome these problems, a team of researchers have reported the creation of Induced Pluripotent Stem (iPS) cells using chemical compounds only and they have termed these cells as CiPS cells. Click to read more...

2. Differentiation process of blood stem cells into macrophages deciphered

Macrophages are immune cells which react against the bacteria and other foreign antigens. Now scientists by observing the differentiation of blood stem cells to white blood cells and macrophages have studied the changes in the key regulatory protein called PU. 1 and have come out with exciting findings. Click to read more...

3. Self organizing blood vessels created from human pluripotent stem cells in a synthetic matrix

Johns Hopkins researchers have reconstructed blood vessels using induced pluripotent stem cells in a hydrogel scaffold. When the hydrogel was loaded with chemical cues, these cues made the cells to organize into a network of recognizable blood vessels which were then transplanted into mice successfully.Click to read more...

4. Study employs Magnets to attract stem cells injected inside the body to the desired location

Novel polyethylene glycol coated iron oxide nanoparticles along with a magnet have been used to track stem cells to the desired location inside the mice in a recent animal study. Click to read more...

5. Genomic imprinting – Mechanism behind maintenance of the quiescent blood stem cell pool in mouse bone marrow

A team led by Linheng Li has explored the role of Genomic imprinting as an additional layer of regulation on the blood stem cell pool, in the journey of blood stem cells from their quiescent reserve cells stage to the stage they form highly specialized cells in the blood lineage. Click to read more...

6. Genes once thought to be indispensable for reprogramming human cells replaced in a novel study.

Salk Institute's scientists have been able to substitute the OCT 4 and SOX 2 genes which were earlier thought to be indispensible in the cocktail for reprogramming adult cells to induced pluripotent stem cells (iPSCs) and this study is expected to hasten the path for iPSCs to reach the clinic. Click to read more...

7. Novel Carbon cloth biomaterial with umbilical cord blood stem cells for generating bone created

A novel biomaterial made up of activated carbon cloth and umbilical cord blood stem cells has been created by scientists which is capable of generating a bone lineage cell product and this in turn will help to form artificial bone tissue.Click to read more...

8. New roles for BMI1 protein in preventing inappropriate stem cell differentiation.

Bmi1 protein which usually serves as a control switch for the self renewal and division of stem cells has been postulated to have a new role of preventing the stem cells to form daughter cells which may mature into the wrong cell type. Click to read more...

9. Gingival stem cells explored

A team led by Dr. Shi has identified that the Gingiva contains 90 percent of mesenchymal stem cells (GMSCs) derived from the cranial neural crest cells (CNCC) and 10 percent derived from mesoderm. This study will pave way for future studies on the interaction between these two types of stem cells and their role in gingival immune defense and wound healing. Click to read more...

10. Embryonic stem cells grown on a three-dimensional synthetic retina restores photoreceptors in night blind mice.

A team of scientists have been able to successfully grow mouse embryonic stem cells in a three-dimensional synthetic retina to form photoreceptors which play a crucial role in sight and when these photoreceptors were transplanted into night-blind mice, a small portion of the cells integrated into the retina of these mice. Click to read more..

Really???

1. Did you know that the oldest description and surgical treatment of the deadly disease 'Cancer', dates to 1500 BC according to a papyrus discovered in Egypt? The Papyrus is termed the Edwin Smith Papyrus, an Egyptian medical treatise and it is dated by some to 3000 BC. It describes '8 cases of tumors or ulcers of the breast that were treated by cauterization with a tool called the fire drill. The writing says about the disease, "There is no treatment."' (Ref: "The History of Cancer". American Cancer Society. 2009.)

2. Did you know that the first Nobel Prize winner in the field of Physiology and Medicine was Emil Adolf von Behring who was awarded the Nobel Prize for the development of serum therapies against diphtheria and tetanus ?

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