CURRENT STEM CELL NEWS

1. Direct conversion of Skin fibroblast cells to skin pigment cells accomplished

Scientists have developed a new methodology to convert skin fibroblasts directly to melanocytes, the pigment producing cells of the skin. This study will help to develop novel therapies for skin diseases like Vitiligo. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. Stem Cell factor based Gene therapy improves cardiac function in pre-clinical models of heart disease

When stem cell factor (SCF) was delivered by gene therapy into pre-clinical models, after inducing heart attack, the gene therapy induced the recruitment c-Kit positive (cKit+) cardiac stem cells to the injury sites which then reversed the heart damage. Click to read more...

3. Immune cells activate hair follicle stem cells, prompting growth of hair –reveals study

A study has identified that macrophages which are immune cells whose main function is to fight infections by engulfing pathogens are also involved in hair regeneration by activating hair follicle stem cells in the skin. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. Stem cells restore mobility in adult rats with symptoms of Parkinson's disease

Scientists have used stem cells to generate dopaminergic nerve cells. These nerve cells when injected into adult rats with symptoms of Parkinson's disease were able to restore mobility. Click to read more...

5. Blood stem cells compromised by High-fat diet and obesity during pregnancy

A study has shown that high-fat diet and obesity during pregnancy compromises the blood-forming stem cells in the fetus. These blood stem cells are the ones which are responsible for formation of the blood and immune system. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. Dual characteristic of nail stem cells revealed

Slow-dividing stem cells of the nail have the ability to perform dual roles reveals a new study, in which these stem cells have been identified to contribute to both nail and adjacent skin under normal circumstances but during injury these stem cells shift their function to exclusively repair the nail. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. Role of specific genes in radiation induced blood stem cell defects studied

When the effects of radiation on the blood stem cells of mice were explored, it has been demonstrated that radiation causes more blood stem cells to become differentiated due to which these cells cannot survive forever. Thus radiation helps in cancer treatment. However some cells with mutated genes escape this effect and these mutated cells dominate the blood system once normal cells are removed, leading to cancer in some patients after radiation. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. Precursor of sperm and eggs created from human embryonic stem cells in a first of its kind study

A team of researchers have reported that the gene known as SOX17 is critical for directing human stem cells to become primordial germ cells which are the precursors to egg and sperm. These researchers have been able to create the primordial germ cells from human embryonic stem cells for the first time. Click to read more... |Click here to view the link of the relevant publication in a peer reviewed journal

9. Receptor protein that regulates blood stem cells engraftment after stem cell transplant identified

Genetic deletion of a protein called PTP-sigma in mice increases the ability of blood stem cells to engraft in transplanted mice, as per a recent report. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. It is stem cells and luck that determines cancer occurrence – shows study

A study has suggested that it is the combination of bad luck and stem cells that might cause cancer. The accumulation of errors in copying of DNA during cell division leads to mutations and to cancer. Since the odds of copying themselves is higher for stem cells, this leads to them being the cause for producing more mutated cells and thereby cancer. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. Are you aware about Fecal Transplant as a therapy? Fecal microbiota transplant (FMT) is a procedure in which healthy donor feces is transferred to a patient during a colonoscopy. By this the healthy bacteria from the transplanted feces go on to colonize the gut combating the overgrowth of pathogenic bacteria thereby helping in cure. Studies have shown that FMT is effective against recurrent Clostridium difficile infections, Irritable Bowel Syndrome, Crohn's Disease, and Ulcerative Colitis.- Source: http://thefecaltransplantfoundation.org/what-is-fecal-transplant | http://articles.mercola.com/sites/articles/archive/2012/10/08/fecal-microbiota-transplant.aspx

2. Did you know when was the first tissue culture experiment conducted? It was in 1885 when Wilhelm Roux a German zoologist maintained a portion of the medullary plate of an embryonic chicken in a warm saline solution for several days.     - Source: Wikipedia

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