CURRENT STEM CELL NEWS

1. Musashi holds the key to Zika virus infectivity- stem cell study reveals

The RNA-binding protein Musashi-1 (MSI1) highly expressed in neural progenitors is the one that interacts with the Zika virus genome and enables viral replication, according to a recent study Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. Handheld printer to print cartilage tissue

Scientists have developed a hand- held 3D printing device called the 'Biopen' which allows printing of cells and bioscaffold directly into the cartilage defect in vivo in a single session surgery. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

3. Treg immune cells regulate hair stem cells – proves study

It has been observed in an animal study, that when immune cells called Tregs are removed from skin, the hair do not regenerate. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. Gene crucial for breast stem cell function identified

A protein called BPTF has been found to be essential for breast stem cell's self-renewal and differentiation into breast epithelial cells. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. Stem cells offer clues to blood vessel development

Tracing the blood vessel cell lineage using human pluripotent stem cell (hPSC) models has helped scientists to understand the various stages of differentiation through which the stem cell passes and this will help to engineer better therapies for vessel diseases. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. Vitamin C and Doxycycline, a lethal combination for cancer stem cells

A new synthetic lethal strategy which combines the antibiotic Doxycycline with Vitamin C has helped to eradicate drug resistant cancer stem cells by Doxycycline targeting mitochondria) and Vitamin C targeting glycolysis. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. Metabolites control stem cell pluripotency – says study

It has been identified that embryonic stem cell (ESC) pluripotency is dependent on relative levels of two metabolites,vitamin C and l-proline as these metabolites control global DNA methylation, transcriptional profile, and energy metabolism. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. Stem cells coaxed to become blood cells by novel approach

Seven transcription factors has been identified to be sufficient to convert blood endothelium into blood stem and progenitor cells and this could be useful in treating genetic blood disorders Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. Psychomotor retardation modelled using iPS cells

Allan-Herndon-Dudley syndrome (AHDS), a psychomotor disease which is due to a defective gene that controls entry of thryoid hormone into the brain resulting from a defective gene that controls the influx of thyroid hormones to the brain has been modelled in the laboratory using patient-specific induced pluripotent stem cells (iPSCs). Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. iPS based approach to treat neural tube defects

Three-dimensional skin grafts generated from skin cells derived from a patient with Down syndrome (AF-T21-iPSCs) and twin-twin transfusion syndrome has been used to cover neural tube defects in utero. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. Did you know Yoga actually acts at a molecular level? Yes, mind–body interventions (MBIs) like Yoga, Tai Chi, Qigong, relaxation response, and breath regulation actually have been found to downregulate a signalling pathway called nuclear factor kappa B pathway which results in reduced risk of inflammation-related diseases, as per a recent scientific study
 -Source: ScienceDaily, 15 June 2017 and Frontiers in Immunology, 2017; 8 DOI: 10.3389/fimmu.2017.00670

2. Are you aware that even 11 dimensional (11D) networks exist in the human brain? Algebraic topological study of brain networks has identified that when each neuron connects to every other neuron in the group to generate a precise geometric object, it can result in some networks having upto eleven dimensions.    
-Source: ScienceDaily, 12 June 2017 and Frontiers in Computational Neuroscience, 2017; 11 DOI: 10.3389/fncom.2017.00048

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