CURRENT STEM CELL NEWS

1. Long-lived dormant stem cell in breast glands which can cause breast cancer identified

Advanced cellular, bioinformatics and imaging technology has helped scientists identify a dormant type of stem cell in the breast which can be activated by ovarian hormones and these cells are behind growth of the mammary glands during pregnancy and may be linked to breast cancer. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. Fat stem cells more stable than age-matched fibroblasts - reveals study

It has been identified that fat derived stem cells make more protein and are more stable than age-matched fibroblasts making them more effective candidates for anti-aging therapies. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

3. Long term results of clinical trial of blood stem cell transplant for multiple sclerosis shows positive outcome

Results of a multicenter clinical trial on blood stem cell transplantation for the treatment of multiple sclerosis has shown that almost half of the patients remained free from neurological progression for 5 years after transplant. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. Ear's inner hair stem cells grown by small molecule drug treatment

Using a small-molecule approach, inner hair stem cells expressing and maintaining Lgr5, an epithelial stem cell marker have been grown to large quantities which in the future could be used for hearing loss treatments. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. Utility of a special type of fat stem cell explored

Stromal vascular fraction (SVF), a stem cell enriched fat cell derived cell population has been explored to use its potential in regenerative treatments as these cells has ability to secrete paracrine factors that can accelerate repair of body tissues and is easily accessible without having major adverse effects. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. Vitamin C kills cancer stem cells – study shows solid proof

A study has shown the first evidence of Vitamin C being ten times more effective in stopping cancer cell stem growth than pharmaceuticals. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. Central role of KLF4 factor in iPS reprogramming explored

The function of the reprogramming factor KLF4 in production of induced pluripotent stem cells (iPSCs) has been explored and it has been identified that this factor controls a crucial metabolic change in energy generation during the acquisition of cellular pluripotency. Click to read more... | Click here to view the link of the relevant publication

8. Stem cells self organize to form embryos in lab

In a study, mouse embryonic and extra-embryonic stem cells when grown in a gel, were shown to self- organize into primitive embryos that perfectly replicated the normal development in the womb. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. Caspase based suicide switch to make iPS cell therapies safe

To make iPS cell therapies safer, researchers have used an inducible caspase system to cause apoptosis or cell death in tumor cells derived from human induced pluripotent stem cells (iPSCs) in a mouse model. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. Clinical trial finds stem cell transplants in Type I Diabetes safe and promising

Results of a clinical trial in Type I diabetes patients who underwent autologous blood stem cell transplant has shown that this form of treatment increased the C-peptide levels and induced insulin independence in these patients for a longer period of time by working on the immune system. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. A brain imaging study has now shown that by identifying specific brain responses, it can be judged whether the person showing the brain response is aware that he/she is committing a crime or instead is acting recklessly. This is an important finding in the emerging field of "neurolaw," which connects neuroscience to legal standards    
 -Source: ScienceDaily, 13 March 2017 and PNAS 2017; DOI: 10.1073/pnas.1619385114

2. Dental plaque can trap microorganisms of the mouth and the gastrointestinal tract preserving the DNA for thousands of years. Study of Dental plaque of Neandertals who are the nearest extinct relative of humans has revealed that Neandertals possessed a good knowledge of medicinal plants and seem to be self-medicating. Particularly, they used antibiotics which is very surprising as Neanderthal period is more than 40,000 years before penicillin was discovered.    
-Source: ScienceDaily, 8 March 2017 and Nature. 2017 Mar 8. doi: 10.1038/nature21674

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