CURRENT STEM CELL NEWS

1. 20-year impact of human embryonic stem cells reported

The 20 year scientific, economic, and clinically relevant impact of human embryonic stem cells has been reflected in a recent publication to commemorate the 20th anniversary of the seminal human embryonic stem cell (hESC) publication, which reported the initial hESC derivations. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. Neural precursors give hope for cerebral palsy

Neural precursor cells (NPCs) when transplanted into a hemiplegic mouse model of neonatal hypoxia-ischemia that recapitulates cerebral palsy (CP) were observed to survive, engraft and differentiate morphologically in male and female mice. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

3. GVHD reduces HIV viral load- says study

Allogeneic hematopoietic stem cell transplant (Allo-HSCT) has been found to result in a profound long-term reduction in the HIV reservoir with this effect being attributed to factors as stem cell source, conditioning, and a possible "graft-versus-HIV-reservoir" effect. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. Chemotherapy induces leukaemia relapse

Cytotoxic chemotherapies put patients at risk for future hematopoietic malignancies as PPM1D mutations caused by chemotherapeutic agents confer a survival advantage onto blood stem cell clones making them resistant to DNA-damaging agents such as cisplatin.Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. Stem cells share memory of past events with immune cells

New studies suggest that stem cells in partnership with the immune system use the memory of immune cells to improve the responses of tissues to later injuries and pathogenic assaults. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. Stem cell trial shows positive results in lupus patients

A single infusion of mesenchymal stem cells (MSCs) has shown to decrease the number of auto-reactive immune cells in systemic lupus erythematosus (SLE) patients. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. iPSCs tested in Parkinson Patient

Dopaminergic-neuron precursors was reprogrammed from donor's skin cell and implanted into the brain of a patient with Parkinson's disease for the first time. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. New Drug Approach targets protein metabolism of cancer stem cells

Leukemia stem cells (LSCs) rely on amino acids for survival. Hence clinically relevant eradication of these LSCs can be achieved with drugs that target LSC metabolic vulnerabilities, according to a recent study. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. Transplant organoids instead of cells for better regeneration

Researchers report that growing cells into a miniature, brain-like organoid and transplanting them into young mice was superior to transplanting individual neural progenitor cells. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. Scaffolds to boost stem cell based regeneration in brain

A biodegradable hybrid inorganic (BHI) nanoscaffold has been employed to increase the survival rate of transplanted neural stem cells and for better control of stem cell fate in vivo. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. A series of experiments have suggested that merely believing that we're multitasking may boost our performance by making us more engaged in the tasks at hand thus hinting that multitasking is often a matter of perception .
 -Source: ScienceDaily, 13 November 2018 & Psychological Science, 2018; 095679761880101 DOI: 10.1177/0956797618801013

2. In line with the famous idiom "go with your gut" a new study has shown that gut bacteria actually control neurons that aid movement in fruit flies.     
-Source: ScienceDaily. ScienceDaily, 1 November 2018 & Nature, 2018; DOI: 10.1038/s41586-018-0634-9

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