CURRENT STEM CELL NEWS

1. Factor that help mesenchymal stem cells survive in low-oxygen environments explored

A team of researchers have identified that the factor SDF-1 activates autophagy in the mesenchymal stem cells thereby helping them survive the low oxygen environment in the bone marrow niche. Further exploring this factor may help in designing strategies for bone repair after fracture. Click to read more...

2. Hybrid human-mouse teeth created using stem cell technology

Hybrid teeth have been created using cells from the human gum tissue and stem cells from mouse teeth and examination of these teeth showed that they contained enamel, dentin and viable root which are all components of a tooth. Click to read more...

3. Origin of ovarian carcinoma traced to stem cells in the hilum region

As a possible clue to where the deadly ovarian cancer originates, it has been discovered that the ovarian carcinoma preferentially originates from stem cells found in the transitional zone called hilum that connects the ovary to the rest of the body.Click to read more...

4. Protein that acts as a barrier to reprogramming of adult cells to pluripotency deciphered

A histone variant protein called macroH2A may act as a barrier to the plasticity of cells thereby making them difficult to be reprogrammed, according to a study led by Dr. Emily Bernstein and her team at Mount Sinai. Click to read more...

5. Combining oxygen chamber treatment with Stem cells may help treat diabetes- suggest study

Scientist from University of Pennsylvania School of Medicine have treated type II Diabetic patients with autologous stem cells and hyperbaric oxygen therapy with promising results. Click to read more...

6. Removing genetic roadblocks may improve reprogramming of cells - suggests study

Scientists have identified that the gene called Jmjd3 is an important roadblock in the reprogramming process and knocking-out or deleting that gene greatly enhanced reprogramming efficiency in young mouse fibroblasts. Click to read more...

7. Gene therapy coupled with Induced pluripotent stem cell technology to offer a potential solution for muscular dystrophy

In a study published in Nature Communications, Scientists have described their work on muscular dystrophy as to how they first generated induced pluripotent stem cells from the skin cells of mice carrying mutations in the dystrophin and utrophin gene and then corrected the gene defect and transplanted the cells back to the mice with gene defect. The transplanted cells generated functional muscle and responded to muscle fibre injury in these mice. Click to read more...

8. Novel population of genetically stable pluripotent somatic cells discovered from breast tissue

Scientists have discovered the presence of pluripotent stem cells in the adult breast tissue which has the ability to differentiate into several cell types. These endogenous pluripotent somatic (ePS) cells due to their genetic stability will be advantageous than embryonic stem cells.Click to read more...

9. Study offers insights into the process of how specialized immune cells eat up neural stem cells in developing brains

It has been found in a study that immune cells called microglia eat up developing neural stem cells in the brain and this process is essential to prevent the unchecked growth of brain tissue. Click to read more...

10. Reprogramming technology to create tumour specific cytotoxic T lymphocytes in large numbers

To create large number of tumour specific cytotoxic T lymphocytes (CTLs), researchers have used the induced pluripotent stem cell technology to convert a melanoma antigen specific T lymphocyte cells from a cell line to iPS cells and then back to melanoma antigen specific T cells with the same cytotoxic capability as the parent T cell. Click to read more..

Really???

1. Do you know what a Respirocyte is? It is a hypothetical microscopic artificial red blood cell which is proposed to be designed as a spherical nanorobot made up of 18 billion atoms in the form of tiny pressure tank so that they can be filled with oxygen and carbon dioxide with ability to make one complete transfer point at the lungs and another transfer point at the body tissues.

2. Did you know that researchers have identified that Yo-Yo dieting (repeatedly losing and regaining weight) actually weakens the immune system by decreasing the NK cell functionality?

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