CURRENT STEM CELL NEWS

1. Crucial role of molecule behind faultless embryonic stem cell differentiation uncovered

Researchers have identified how a molecule called Fbxl10 plays an important role in the silencing of genes involved in embryonic stem cells leading to differentiation of these cells and this in the future will serve to identify potential anti- cancer therapeutic targets. Click to read more...

2. Stem cells recycle themselves for survival- suggests study

Autophagy or self eating by reusing molecules protects stem cells in times of metabolic stress and allows them to avoid the alternate stress response, which is programmed cell death, according to a recent study published in the journal ‘Nature’. Click to read more...

3. 3D printing of embryonic stem cells opens new avenues in stem cell science

A team of scientists have successfully printed Human embryonic stem cells using 3D printing technology and this will pave way for creating improved in vitro human tissue models for drug testing and also artificial organ development.Click to read more...

4. Stem cells and nanotopographical cues to offer novel solutions for bone regeneration

Scientists from University of Southampton have employed nanotopographical cues on substrates to manipulate human embryonic stem cells for differentiation towards bone cells and this will help improving bone regeneration. Click to read more...

5. Molecular pathways involved in cross talk behind two groups of stem cells in the hair deciphered

Crosstalk between two populations of stem cells residing in the hair, the hair follicle stem cells and melanocyte stem cells is essential for proper hair regeneration and hair colour. Researchers have studied the important mediators involved in proper synchronization of activity of these two stem cell populations in mice. Click to read more...

6. A step forward in Research on ‘disease in dish’ methodology using iPSC for an inherited heart disease

Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is a rare inherited heart disease and scientists have used iPSC technology to create patient specific iPS cells from patients with ARVD/C and they found that the disease was recapitulated in vitro only if the young heart cells derived from these iPS cells are manipulated to adapt to adult heart cell metabolism. Click to read more...

7. Potential Biomaterial for maintaining neuronal cells and recapitulating the neural progenitor niche identified

A team from University of Barcelona has tested types of polylactic acid (PLA) with different proportions of the isomers L and D/L to identify the most optimal scaffold for recapitulating the neural stem cell niche. Click to read more...

8. Patient specific iPS cells can overcome issues of immune rejection- suggests study

A new study has shown that transplantation of differentiated cells produced from iPS in genetically identical experimental models had no issues of immunorejection thus showing promising applications for iPS derived cells in the future.Click to read more...

9. Studying telomeric DNA in cancer cells to offer significant clues for understanding cancer

In a novel attempt in Cancer biology, Researchers have linked the changes in the volume of telomeric DNA to particular types of cancer and their associated genetic mistakes. Click to read more...

10. Bone Marrow stromal cells serve as ideal niche for Tuberculosis bacterium to reside for long even after drug therapy

Tuberculosis bacterium can lie dormant in bone marrow mesenchymal stem cells for long periods of time even after treatment according to a new study. This might be important in the process of reactivation of the disease as these stem cells migrate to regions of inflammation and start dividing which might cause recurrence of the disease. Click to read more..

Really???

1. Paradoxes in biology are always interesting. One of them is the Peto’s Paradox which tells that cancer does not correspond to the number of cells in an organism. For eg, humans get more cancer than large mammals like whales. This may be due to the fact that evolution of multicellularity required more cancer suppression.

2. Among the weird gene names, special mention is to be made to the ‘RING’ gene which got its name because its discoverers didn’t initially know what the function of this gene in Drosophila is and hence named the gene “Really Interesting New Gene” (RING). (Source: http://tinman.nikunnakki.info/browser)

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