CURRENT STEM CELL NEWS

1. New genes that direct cell fate of blood forming progenitor cells in fruit fly explored

Researchers have found that two unique genes Yorkie and Scalloped are implicated in progenitor cell differentiation. Absences of these genes affected the immune cell differentiation from these progenitor cells. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. Early stages of mammalian development modeled using embryonic stem cells in the lab

By activating some specific signals on mouse embryonic stem cells, Scientists have recapitulated the gastrulation stage with spatial organization, axis formation and early gastrulation movement in-vitro. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal | Click here to view the link of the relevant publication in a peer reviewed journal

3. Anti-inflammatory drugs protect against colon cancer by inducing cell suicide in intestinal stem cells – reveals study

The mechanism behind anti-inflammatory drugs protecting against colon cancer has been identified due to the apoptosis or cell suicide induced by these drugs in the intestinal stem cells that carry a particular gene mutation. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. Role of 'FAK' molecule in breast cancer stem cells and breast cancer recurrence investigated

A team of researchers have investigated the role of a molecule known as FAK in the treatment resistance of a particular form of breast cancer known as DCIS. They have observed that the cancer stem cells in these cancers had increased levels of FAK and blocking the FAK improves the cancer's sensitivity to radiotherapy. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. Fully functional mini stomach created in lab using pluripotent stem cells

To study Gastric diseases in vitro, scientists have created three dimensional structures of miniature stomachs using human pluripotent stem cells. In these 3D structures known as gastric organoids, when H. pylori was introduced, a replication of the early stages of gastric disease was observed. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. New Gene editing technique to block HIV

Using CRISPR Cas technology, a group of scientists have been able to efficiently and precisely edit clinically relevant genes oin human blood forming stem cells and T-cells so that these cells can act against HIV virus without becoming suscepitible to it. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. Molecular steps involved in development of pancreatic cancer deciphered

Researchers have now identified the molecular steps in pancreatic cancer development. They have reported that Kras proteins in the acinar cells induce the expression of a molecule called ICAM-1, which attracts immune cells called macrophages which in turn secrete proteins that turn these acinar cells into ones that drive pancreatic cancer development. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. Scientists directly create neural stem cells from liver cells and lymphocytes

Scientists have created induced neural stem cells (iNSCs) from adult cells and since these iNSCs have the capability to remain in the multi-potent state without ongoing expression of reprogramming factors, they can divide repeatedly to generate cells sufficient for therapy. Click to read more... |Click here to view the link of the relevant publication in a peer reviewed journal

9. Dopamine secreting neurons developed from embryonic stem cells and transplanted to rats – Hops to treat Parkinson's disease

Stem Cell transplants for Parkinson's disease have moved a step forward as researchers have been able to create dopamine neurons from human embryonic stem cells which showed similar efficacy to fetal neurons when grafted in a rat model of Parkinson's Disease. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. Functional human tendons grown in a bioreactor in lab for the first time

Researchers have been able to grow functional human tendons in a bioreactor in the laboratory and these tendons will be potentially useful in treating various injury sites such as tennis elbow, Achilles and patellar tendons. Click to read more...

Really???

1. Are you aware that Scientists from Johns Hopkins University have identified that the algae virus called "chlorovirus ATCV-1" is also capable of infecting humans and the disturbing fact is that when a mice model was infected with this virus they displayed deficits in cognitive function? Scientists now believe that this virus could affect cognitive function in humans too.

2. Did you know that viruses drive evolution as they are an important natural means of horizontal gene transfer between different species which increases genetic diversity and thereby drive evolution? The genetic diversity of viruses still remains largely unexplored.

                                                                                                                            - Source: Wikipedia

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