CURRENT STEM CELL NEWS

1. Tracing the genomic Imprint erasures and re-programming of genes in human germ cells.

A study published in Nature Biology has shown what happens to the genes during the early development of the embryo, as to how the genomic imprints of the parents transferred to the cells of the embryo are erased, how the genes are re-programmed etc. thus providing a valuable insight into the human developmental process. Click to read more...

2. HER2 positive cancer stem cells identified in HER2 negative breast cancers – gives hope to patients

A team lead by Jian Jian Li from the UC Davis Department of Radiation Oncology has identified treatment resistant HER2 positive cancer stem cells in HER2 negative breast cancer patients thus changing the present understanding of this type of breast cancer and proving that HER2-negative breast cancers can be indeed treated effectively with anti-HER2 treatments. Click to read more...

3.Synthetic foams with randomly distributed sticky spots created for stem cell adhesion and growth

Scientists have created a synthetic foam type material with two polymers, one sticky and the other not sticky separated from each other in a solution so as to create randomly distributed nano-scopic patches of the sticky material in a non-sticky material. The scientists found that this kind of random stickiness versus uniform stickiness was required for stem cells to properly adhere and undergo maturation.Click to read more...

4. Cancer stem cells isolated from Wilms' tumour- new avenues for novel therapeutic approaches

In a first of its kind study in Paediatric tumours, researchers from Israel have isolated the cancer stem cells from Wilms’ tumour, a kind of tumour that occurs in the kidney of children and have used the stem cells to create animal models to study the development of this cancer and novel therapeutic targets to tackle it.Click to read more...

5. Novel membranes for grafting of stem cells in the eye developed

Engineers from the University of Sheffield have developed novel biodegradable membrane discs using microstereolithography and electrospinning techniques and these biodegradable membranes will be helpful as carrier of stem cells during transplantation to the cornea. Click to read more...

6. Single gene to create biological pacemakers – A scientific feat

Researchers from Cedars-Sinai Heart Institute have used a single gene to reprogram heart cells to pacemaker cells that generate electrical activity which spreads to other heart cells to create rhythmic muscle contractions of the heart. Click to read more...

7. Leukemic stem cells continue to foster genomic aberrations- says study

A new research has identified that even during treatment with Imatinib, stem cells in chronic myeloid leukemia that become resistant to this drug continue to foster DNA damage and genomic aberrations that leads to relapse of the disease later. Thus combining a drug that can stop these genetic aberrations during treatment with Imatinib may be a potential solution.Click to read more...

8. Adult neurogenesis controlled by lipid metabolism

The division of neural stem cells depends on lipid metabolism, according to a study led by Prof. Sebastian Jessberger. When a key enzyme of this pathway named Fasn is blocked, the stem cells lose their ability to divide. These stem cells are prevented from constant division by a protein called Spot14 which inhibits the lipid synthesis.Click to read more...

9. A prostaglandin to accelerate blood stem cell division to aid in marrow recovery after myelosuppression

Scientists from University of Rochester Medical Center have employed a prostaglandin called PGE2 to accelerate blood stem cell division to aid in the recovery of the marrow after myelosuppression due to chemotherapy or radiotherapy. Early treatment with PGE2 helps not only in proliferation of new healthy blood cells but also in slowing death of blood cells in response to radiation. Click to read more...

10. Safety of Autologous Stem Cell Therapy in chronic ischemic stroke established by clinical study from India

A clinical study on injection of autologous bone marrow stem cells in 24 patients with chronic ischemic stroke (CIS) has shown that this cell therapy is safe and cell therapy combined with physiotherapy led to a trend of improvement in clinical and fMRI scores at 8 weeks as compared to physiotherapy alone and these changes lasted till 24 weeks. Click to read more..

Really???

1. Did you know that Mimivirus possess the largest viral genome known in scientific knowledge, comparable to bacterial genome and they code for products which were previously not thought to be encoded by viruses? These viruses were first mistaken to be bacteria and later identified to be viruses. They have also been added to the debate over the origin of life due to their unique genes and old lineage.

2. Are you aware about the term ‘Genetic erosion’? It is the term to describe the process of loss of particular alleles or genes in organisms which don’t get a chance to breed. This is of particular significance to endangered species which will already have only a limited gene pool which will diminish further when they don’t get a chance to breed. Genetic erosion leads to in-breeding and weakened immune systems leading to species extinction rapidly.

Creative Commons License All site content, except where otherwise noted is licensed under a Creative Commons Attribution 3.0 Unported License.