CURRENT STEM CELL NEWS

1. Brain tissue printed using novel 3D printing technology and stem cells

A polysaccharide-based bioink has been used to bioprint human iPSCs which could differentiate into all the three germ layers and also could form functional migrating neurons. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. iPSC cells provide clue to mechanisms underlying Schizophrenia

A iPSC based study has identified that glial cell dysfunction may be the basis of childhood-onset schizophrenia. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

3. Glioma stem cells' role in Brain tumour explored

A molecular mechanism that maintains glioma stem cells in the brain tumour, Glioblastoma has been identified and researchers have tries a synthetic small molecule inhibitor designed by them that acts against the mechanism. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. Brain stem cells control aging through exosomes- says study

It has been shown that the stem cells of the brain in the hypothalamus control the speed of aging through the release of exosomal miRNAs. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. Engineered stem cells as vehicles for cancer drug delivery

Since cancer tissues are stiffer than normal tissues, scientists have used mechanoresponsive stem cells that pick up this stiffness as cues to get attracted to the tumours to deliver the drug that has been loaded in them. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. Autologous stem cells need to be modified before transplantation in heart failure patients- says study

Researchers have identified that when patients' when cardiac stem cells are used to repair damaged heart tissue the cells may not only be ineffective but may actually worsen the disease due to their inflammatory characteristics. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. Cell free Nano-medicine based approach to treat multiple sclerosis

Nano-medicine (NanoMed) based targeted delivery of growth factor which will activate resident brain stem cells for endogenous repair will be the future to treat neurodegenerative diseases like multiple sclerosis according to a recent review. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. Grape-seed extract to kill colon cancer stem cells

The combination of resveratrol (RSV) a grape bioactive compound and grape seed extract can be very effective in treating colon cancer as per a study and the mechanism has been attributed to suppression of Wnt/β-catenin signalling and elevated mitochondrial-mediated apoptosis in the cancer stem cells. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. Brain stem cells have distinct regional identity- proves study

Hypothalamus, a brain area that regulates physiological states has been observed to provide regionalized input to localize specific brain stem cell populations in response to physiology and environmental signals. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. Miniature eyes developed in the lab

Miniature eye-like organs that closely resemble the developing eyes of an early-stage embryo have been created in the lab using induced pluripotent stem (iPS) cells. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. Researchers who raised 200 generations of fruit flies to study the pattern of mutation along with studying fossil evidence and conducting DNA sequencing have discovered that even insignificant mutations can predict up to 40 million years of evolution as the pattern of mutation has remained almost constant over that time period.
 -Source: ScienceDaily, 9 August 2017 and Nature, 2017; DOI: 10.1038/nature23473

2. Taste responses of the tongue which are key to survival (Sweet tastes can signal nutrient density while whereas bitter tastes can signal a deadly poison) are actually sensed properly by the tongue by virtue of specific chemical signals in the frequently newborn taste receptor cells that pull the right nerve cell connections toward them, creating proper networks to the brain leading to proper taste sensation.    
-Source: ScienceDaily, 9 August 2017 and Nature, 2017; DOI: 10.1038/nature23299

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