CURRENT STEM CELL NEWS

1. Heart stem cells' function can be enhanced by spaceflight reports study

Using simulated microgravity (SMG) aboard the International Space Station (ISS), researchers have studied cardiovascular progenitor cell development and signaling in which it has been identified that under such environmental conditions, there is increased expression of genes associated with an earlier state of cardiovascular development. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

2. Mechanism behind resistance of stem cells to viral infection identified

The high resistance of stem cells to viral infection compared to their differentiated progeny has been identified due to the increased expression of interferon (IFN) stimulated genes (ISGs). Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

3. RPE cell patch tested in human clinical study

3. RPE cell patch derived from fully differentiated, human embryonic stem cells (hESC) has been used to improve vision in two human patients with Age-related macular degeneration (AMD). Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

4. Integrating single cell RNA sequences using novel strategy

An analytical strategy has been developed for integrating Computational single-cell RNA-seq (scRNA-seq) data sets that can 'align' multiple sequencing datasets with single-cell resolution. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

5. Ways to improve performance of bioengineered human heart cells explored

Researchers have generated a a model of human adult-like cardiac muscle from induced pluripotent stem cells (iPSC) with better functionality by introducing electric and mechanical stimulation at an early stage.Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

6. Cell therapy combined with ROCK inhibitor for Corneal endothelial diseases

Injection of human Corneal endothelial cells (CECs) supplemented with a ROCK inhibitor has helped in an increase in the CEC density after 24 weeks in human patients with bullous keratopathy. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

7. Lysosomal stimulation to make neural stem cells young

A study has shown that stimulating lysosomal function allows aged quiescent neural stem cells to clear protein aggregates which restores the cells' ability to be activated. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

8. Universal probe for cancer stem cells developed

Researchers have developed a new fluorescent dye that selectively stains cancer stem cells from a broad variety of cancers. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

9. Cellular source of renewing liver cells discovered

Rare hepatocytes with high telomerase expression have been discovered to be distributed throughout the liver lobule and these cells have been observed to regenerate hepatocytes in all zones of the liver. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

10. Ribosome levels regulate cellular differentiation

By studying a genetic blood disorder, Diamond-Blackfan anemia (DBA), scientists have found that global reduction in ribosome levels alters translation of a select subset of transcripts and this in turn impairs red blood cell lineage commitment. Click to read more... | Click here to view the link of the relevant publication in a peer reviewed journal

Really???

1. Studying the bony labyrinth of the inner ear can provide information about the global dispersal of humans from Africa, says a recent study in which it has been studied that the further away a population is geographically from South Africa, the more the shape of the labyrinth differs from that of the South African population.
 -Source: ScienceDaily, 3 April 2018 and Proceedings of the National Academy of Sciences, 2018; 201717873

2. Did you know that there is a bacterial species that essentially 'breathe' rocks? Shewanella oneidensis, a species of bacteria have developed a way to transfer electrons from the interior of the cell across their outer membrane to a receiving surface in the outside world and this process when studied in depth can provide a foundation for sustainable energy in the future.     
-Source: ScienceDaily, 30 March 2018 and Proceedings of the National Academy of Sciences, 2018; 201718810

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