Vol. VII Issue: 3 (Special Issue)
Abstracts of the 2nd Meeting of the Asian Cellular Therapy Organization
(PACTO 2011)
ORAL PRESENTATION
TRANSPLANTATION 1
(O1) A suitable conditioning regimen in allogeneic hematopoietic stem cell transplantation for adult patients with acute lymphoblastic leukemia
Masahiro Imamura (PACTO 2011-O-001)
2011 Vol. 7 (3): p98 [HTML]
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JSRM Code: 007030700023
(O2) Haploidentica lFamily Donor for Hematopoietic Transplantation to Treat High Risk Hematological Diseases in Adult
Ming Yao, Shang-Ju Wu, Jih-Luh Tang,Yao-Chang Chen (PACTO 2011-O-002)
2011 Vol. 7 (3): p99 [HTML]
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JSRM Code: 007030700024
(O3) Hematopoietic stem cell transplantation in China
Kaiyan LIU (PACTO 2011-O-003)
2011 Vol. 7 (3): p100 [HTML]
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JSRM Code: 007030700025
TRANSPLANTATION 2
(O4) Depletion of Alloreactive T cells for Tolerance Induction in a Recipient of Kidney and Hematopoietic Stem Cell Transplantations
Kanjana Tangnararatchakit, Wiwat Teerapanich, Usanarat Anurathapan, Wiwat Tapaneeyaolarn, Samart Pakakasama, Saengsuree Jootar, Shimon Slavin, Suradej Hongeng (PACTO 2011-O-004)
2011 Vol. 7 (3): p101 [HTML]
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JSRM Code: 007030700026
(O5) Current Status of Hematopoietic Stem Cell Transplantation (HSCT) in India
Banavali S(PACTO 2011-O-005)
2011 Vol. 7 (3): p102 [HTML]
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JSRM Code: 007030700027
(O6) Introduction of WHO-WBMT Vietnam Workshop 2011
Yoshihisa Kodera (PACTO 2011-O-006)
2011 Vol. 7 (3): p103 [HTML]
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JSRM Code: 007030700028
NEW STRATEGY OF TRANSPLANTATION
(O7) Autologous hematopoietic stem cell transplantation in the treatment of severe autoimmune disease
Hiroshi Tsukamoto (PACTO 2011-O-007)
2011 Vol. 7 (3): p104 [HTML]
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JSRM Code: 007030700029
(O8) The use of Mesenchymal Stromal Cells to modulate Immune Responses: Risk and Benefit
Willem E Fibbe (PACTO 2011-O-008)
2011 Vol. 7 (3): p105 [HTML]
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JSRM Code: 007030700030
(O9) Nonhomologous Hematopoietic Cell Therapy
Edwin M. Horwitz (PACTO 2011-O-009)
2011 Vol. 7 (3): p106 [HTML]
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JSRM Code: 007030700031
IMMUNOTHERAPY 1
(O10) New strategy of adoptive-immunotherapy using γ δ T cells
Hirohito Kobayashi(PACTO 2011-O-010)
2011 Vol. 7 (3): p107 [HTML]
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JSRM Code: 007030700032
(O11) Autologous T cell Therapy Against Tumors
Jaeseung Lim(PACTO 2011-O-011)
2011 Vol. 7 (3): p108 [HTML]
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JSRM Code: 007030700033
(O12) Ex vivo - expanded allogeneic natural killer cells for clinical application in anti-tumor immunotherapy
Yu-Kyeong Hwang (PACTO 2011-O-012)
2011 Vol. 7 (3): p109 [HTML]
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JSRM Code: 007030700034
IMMUNOTHERAPY 2
(O13) Dendritic Cell Immunotherapy of Gastrointestinal Tumors
H. Kim Lyerly (PACTO 2011-O-013)
2011 Vol. 7 (3): p110 [HTML]
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JSRM Code: 007030700035
(O14) Immunotherapy for the Treatment of Advanced Prostate Cancer
Mark W. Frohlich (PACTO 2011-O-014)
2011 Vol. 7 (3): p111 [HTML]
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JSRM Code: 007030700036
(O15) Clinical translation of Chimeric Antigen Receptor (CAR) messenger RNA (mRNA) loaded T- and NK-cell immunotherapy for safe, tumor-targeted bioactivity
Madhusudan V. Peshwa (PACTO 2011-O-015)
2011 Vol. 7 (3): p112 [HTML]
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JSRM Code: 007030700037
MESENCHYMAL STEM CELLS
(O16) Systemic MSC Therapy for Genetic and Acquired Orthopedic Disorders
Satoru Otsuru (PACTO 2011-O-016)
2011 Vol. 7 (3): p113 [HTML]
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JSRM Code: 007030700038
(O17) Mechanisms of MSC (mesenchymal stem cell) accumulation at the sites of tumors
Ryosuke Uchibori, Keiya Ozawa (PACTO 2011-O-017)
2011 Vol. 7 (3): p114 [HTML]
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JSRM Code: 007030700039
(O18) Oncolytic measles virus-loaded human bone marrow-derived mesenchymal stem cells as systemic cancer therapeutic agents for human hepatocellular carcinoma
Ong HT, Federspiel MJ, Russell SJ,Peng KW and Hui KM (PACTO 2011-O-018)
2011 Vol. 7 (3): p115 [HTML]
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JSRM Code: 007030700040
GENE THERAPY
(O19) Phase-I trial of T cell-depleted haplo-identical stem cell transplantation (Haplo-SCT) combined with HSV-TK gene modified T cell add-back
Yuji Heike, Takako Wakeda, Takahiro Fukuda, Shinichiro Mori, IkueiNukaya, Jun-ichiMineno, Kazuto Takesako and Yoich Takaue (PACTO 2011-O-019)
2011 Vol. 7 (3): p116 [HTML]
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JSRM Code: 007030700041
(O20) Engineered T Cell Immunotherapy for Cancer in Japan
Kazuto Takesako (PACTO 2011-O-020)
2011 Vol. 7 (3): p117 [HTML]
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JSRM Code: 007030700042
(O21) Adoptive T-Cell Therapy for Cancer from the Benchtop to the Bedside and beyond
Renier J Brentjens (PACTO 2011-O-021)
2011 Vol. 7 (3): p118 [HTML]
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JSRM Code: 007030700043
REGENERATIVE MEDICINE
(O22) Cartilage Repair -Past, Present and Future
Mitsuo Ochi (PACTO 2011-O-022)
2011 Vol. 7 (3): p119 [HTML]
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JSRM Code: 007030700044
(O23) Strategies for addressing stand-alone corneal epithelial and endothelial diseases using in vitro expanded cells using Nano scaffolds and polymers
Abraham S (PACTO 2011-O-023)
2011 Vol. 7 (3): p120 [HTML]
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JSRM Code: 007030700045
(O24) Recent advances in clinical application of human stem cells
Kwang-Hoe Chung, Hyung-Min Chung, Dong Ryul Lee, Jisook Moon, Kwang-Yul Cha (PACTO 2011-O-024)
2011 Vol. 7 (3): p121 [HTML]
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JSRM Code: 007030700046
(O25) Commercialization of allogeneic, off-the-shelf, adult stem cell drug products using human Umbilical Cord Blood-derived Mesenchymal Stem Cells (hUCBMSCs)
Antonio S J Lee (PACTO 2011-O-025)
2011 Vol. 7 (3): p122 [HTML]
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JSRM Code: 007030700047
(O26) Generation of Functional Platelets from Pluripotent Stem Cells
Hiromitsu Nakauchi (PACTO 2011-O-026)
2011 Vol. 7 (3): p123 [HTML]
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JSRM Code: 007030700048
FACILITY
(O27) Transition from standard to cGMP manufacturing in a growing laboratory and transplant service
Lawrence S. Lamb (PACTO 2011-O-027)
2011 Vol. 7 (3): p124 [HTML]
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JSRM Code: 007030700049
(O28) SANYO’S Approach to Aseptic Cell Manufacturing
Sachihiko Kataoka (PACTO 2011-O-028)
2011 Vol. 7 (3): p125 [HTML]
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JSRM Code: 007030700050
(O29) Development of Automated cell processing system R-CPX for regenerative medicine
Katsumi Nakashima (PACTO 2011-O-029)
2011 Vol. 7 (3): p126[HTML]
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JSRM Code: 007030700051
Clinical development in Asia, from CRO point of view
(O30) 1.The current situation of CRO business in Asia
2.Experience of clinical development/study in Asia.
3.Future of clinical development in Asia from CRO point of view
Hidemi Aida(PACTO 2011-O-030)
2011 Vol. 7 (3): p127 [HTML]
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JSRM Code: 007030700052
REGULATORY SESSION 1
(O31) Stem cell therapy in chronic stroke patients-Phase II trial
Shinn-Zong Lin, Demeral Liu, Woei-Cherng Shyu (PACTO 2011-O-031)
2011 Vol. 7 (3): p128 [HTML]
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JSRM Code: 007030700053
REGULATORY SESSION 2
(O32) Unproven stem cell treatments: Moving targets on the global landscape
Douglas Sipp (PACTO 2011-O-032)
2011 Vol. 7 (3): p129 [HTML]
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JSRM Code: 007030700054
REGULATORY SESSION 3
(O33) NK cell therapy for cancer in practice
Jun-ichi Masuyama (PACTO 2011-O-033)
2011 Vol. 7 (3): p130 [HTML]
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JSRM Code: 007030700055
POSTER PRESENTATION
(P1) Modified donor lymphocyte infusion in the prophylaxis of relapse after HLA-mismatched/haploidentical T-cell-replete hematopoietic stem cell transplantation for advanced-stage acute leukemia: a retrospective risk factors analysis
Wang-Yu, Liu Dai-Hong, Xu Lan-Ping, Liu Kai-Yan, Chen Huan, Zhang Xiao-Hui, Chen Yu-Hong, Han Wei, Huang Xiao-Jun (PACTO 2011-P-034)
2011 Vol. 7 (3): p131 [HTML]
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JSRM Code: 007030700056
(P2) Modified donor lymphocyte infusion associated acute graft-versus-host disease after haploidentical T-cell-replete hematopoietic stem cell transplantation: incidence and risk factors
Chen-hua Yan, Dai-hong Liu, Lan-ping Xu, Kai-yan Liu, Ting Zhao, Yu Wang, Huan Chen, Yu-hong Chen, Wei Han, Xiao-jun Huang (PACTO 2011-P-035)
2011 Vol. 7 (3): p132 [HTML]
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JSRM Code: 007030700057
(P3) Lymphoid commitment in human bone marrow CD34-positive cells reflects aging of hematopoietic stem cells.
Yuichi Kodama, Azumi Miyazono, Yasuhiro Okamoto, Yuni Yamaki, Koichiro Kurauchi, Takuro Nishikawa, Takayuki Tanabe, Yuichi Shinkoda, Yoshifumi Kawano (PACTO 2011-P-036)
2011 Vol. 7 (3): p133 [HTML]
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JSRM Code: 007030700058
(P4) The Study on the Source of Engraftment of Mesenchymal Stem Cells in Patients after Different Source of Hematopoietic Stem Cell Transplantation
Jing Wang, Xiao-Jun Huang, Yu-Hong Chen, Lan-ping Xu, Dai-hong Liu, Huan Chen, Rui-Qin Hou, Xiao-Ying Qin, Kai-yan Liu (PACTO 2011-P-037)
2011 Vol. 7 (3): p134 [HTML]
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JSRM Code: 007030700059
(P5) Novel natural killer (NK) -cell expansion system for producing large amount (>109 cells) and high purity (>90%) of CD3+ CD56+ cells
Mitsuko Ideno, Mie Yabuuchi, Meiko Jin, Tatsuji Enoki, Naoyuki Sakamoto, Takeshi Ishikawa, Satoshi Kokura, Junichi Mineno (PACTO 2011-P-038)
2011 Vol. 7 (3): p135 [HTML]
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JSRM Code: 007030700060
(P6) Development of a novel stimulation method to expand CIK cells containing high proportion of CD3+ CD56+ cells
Mitsuko Ideno, Meiko Jin, Tatsuji Enoki, Junichi Mineno (PACTO 2011-P-039)
2011 Vol. 7 (3): p136 [HTML]
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JSRM Code: 007030700061
(P7) Depletion of CD3-positive cells enables to generate purified and expanded human natural killer cells from peripheral blood mononuclear cells showing strong killer activity
Satoru Saito, Yui Harada, Yoshikazu Yonemitsu (PACTO 2011-P-040)
2011 Vol. 7 (3): p137 [HTML]
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JSRM Code: 007030700062
(P8) Effect of Herceptin is increased by ex vivo cultured NK cell via antibody-dependent cellular cytotoxicity (ADCC).
Takako Wakeda, Sul Hee Yoon, Yoshinori Ikarashi, Kazunori Aoki, Tsukasa Shinohara, Yuni Yamaki, Yuji Heike (PACTO 2011-P-041)
2011 Vol. 7 (3): p138 [HTML]
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JSRM Code: 007030700063
(P9) Synergistic anti-cancer effect of large scale simultaneous expanded NK and γ δ T cells with monoclonal antibody drugs
Xuewen Deng, Mie Nieda, Hiroshi Terunuma (PACTO 2011-P-042)
2011 Vol. 7 (3): p139 [HTML]
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JSRM Code: 007030700064
(P10) Requirements for common chain family cytokines for adoptively transferred γ δ T cell function and homeostasis in vivo
Kazuhiro Kakimi, Takamichi Izumi, Makoto Kondo, Nao Fujieda, Atsushi Kondo, Naohisa Tamura, Ryuji Maekawa, Hirokazu Matsushita (PACTO 2011-P-043)
2011 Vol. 7 (3): p140 [HTML]
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JSRM Code: 007030700065
(P11) Immune tolerance induction to FVIII in hemophilia A using autologous endothelia progenitors
Hideto Matsui, David Lillicrap, Mitsuhiko Sugimoto, Midori Shima (PACTO 2011-P-044)
2011 Vol. 7 (3): p141 [HTML]
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JSRM Code: 007030700066
(P12) An Evaluation of CD34+ Cells in the Bone Marrow of various age groups of Indian Population
Abraham S, Manjunath S, Senthilkumar R, Murugan P, Thamaraikannan P, Srinivasan T, Preethy S, Dedeepiya V (PACTO 2011-P-045)
2011 Vol. 7 (3): p142 [HTML]
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JSRM Code: 007030700067
(P13) Sipuleucel-T: Adaptive Immune Response and Product Characterization from the Phase III IMPACT Trial
Nadeem Sheikh, Daniel Petrylak, Christian Poehlein, James Whitmore, Frances Stewart, Corazon dela Rosa, David Urdal (PACTO 2011-P-046)
2011 Vol. 7 (3): p143 [HTML]
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JSRM Code: 007030700068
(P14) Cytokine-based log-scale expansion of functional human dendritic cells from PBMC
Yui Harada, Satoru Saito, Yoshikazu Yonemitsu (PACTO 2011-P-047)
2011 Vol. 7 (3): p144 [HTML]
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JSRM Code: 007030700069
(P15) Efficient antigen presentation by DCs loaded with antigens by electroporation
Koji Nagaoka, Masashi Takahara, Ryuji Maekawa, Takayuki Yoshimoto, Tsuyoshi Teruya, Hiroshi Shiroma (PACTO 2011-P-048)
2011 Vol. 7 (3): p145 [HTML]
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JSRM Code: 007030700070
(P16) Tissue Factor-triggered Procoagulant Activity of Murine/Human Mesenchymal Stem Cells
Kohei Tatsumi, Kazuo Ohashi, Yoshinori Matsubara, Ayako Kohori, Hiroshi Kakidachi, Akihiro Horii, Takanori Iwata, Teruo Okano (PACTO 2011-P-049)
2011 Vol. 7 (3): p146 [HTML]
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JSRM Code: 007030700071
(P17) HLA-G Molecules Are Important In Alleviation Of Acute Lung Injury By Placenta Chorion Mesenchymal Stem Cells (pcMSCs) Therapy In Mice Model
Thai-Yen Ling, Meng-Shiue Wu, Yi-Ting Hsieh, Jo-Chi Hsu, Hung-Chih Lai, Fu-Chuo Peng, Jie-Yang Jhuang, Yao-Chang Chen (PACTO 2011-P-050)
2011 Vol. 7 (3): p147 [HTML]
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JSRM Code: 007030700072
(P18) Useful cell lines (PMDC05/11) of plasmacytoid dendritic cell for cellular immunotherapy
Masuhiro Takahashi, Miwako Narita, Akie Yamahira, Norihiro Watanabe, Shigeo Hashimoto, Yoji Yuki (PACTO 2011-P-051)
2011 Vol. 7 (3): p148 [HTML]
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JSRM Code: 007030700073